SCHEMBL4493840 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	PTGES	O14684	1/20	0.33

▸	GPR84	Q9NQS5	2/20	0.33

▸	PPARG	P37231	2/20	0.33

▸	PPARD	Q03181	2/20	0.33

▸	PPARA	Q07869	2/20	0.33

▸	ALDH1A1	P00352	1/20	0.33

▸	TSHR	P16473	1/20	0.33

▸	SLC22A6	Q4U2R8	1/20	0.33

▸	SLC22A8	Q8TCC7	1/20	0.33

▸	TLR2	O60603	1/20	0.33

▸	HDAC11	Q96DB2	1/20	0.33

▸	TDP1	Q9NUW8	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4498830	0.88	—	—
SCHEMBL4499053	0.73	AGTR1 (0.36)	PTGES
SCHEMBL4493426	0.66	—	—
SCHEMBL31738687	0.59	PLA2G2A (0.58)	GPR84PPARGPPARDPPARAALDH1A1
SCHEMBL7944628	0.59	BID (0.46)	PPARGPPARAALDH1A1
Acetic Acid SCHEMBL9871794	0.59	GPR84 (0.58)	GPR84PPARGPPARDPPARAALDH1A1
SCHEMBL14989207	0.57	BID (0.51)	PPARGPPARAALDH1A1
SCHEMBL19406558	0.57	BID (0.51)	PPARGPPARAALDH1A1
SCHEMBL14989230	0.57	BID (0.51)	PPARGPPARAALDH1A1
SCHEMBL14989136	0.57	BID (0.51)	PPARGPPARAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7504429-B2	Tyrosine kinase inhibitors	MERCK & CO., INC. (US)	2009-03-17	—	—	US	claimed