SCHEMBL4494028

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Methanesulfonamide SCHEMBL4500516	0.86	MEN1 (0.49)	MAPTSMN1; SMN2HPGDKMT2AMEN1
	Benzenesulfonamide SCHEMBL4496281	0.85	MEN1 (0.48)	MAPTSMN1; SMN2HPGDKMT2AMEN1
	SCHEMBL5203048	0.85	MEN1 (0.54)	MAPTSMN1; SMN2HPGDKMT2AMEN1
	SCHEMBL5207437	0.76	MEN1 (0.64)	MAPTSMN1; SMN2HTTHPGDKMT2A
	SCHEMBL5208537	0.74	LMNA (0.48)	MAPTSMN1; SMN2HPGDNPC1KMT2A
	SCHEMBL13973636	0.71	MAPK10 (0.51)	MAPTSMN1; SMN2HTTNPC1ALDH1A1
	SCHEMBL5205074	0.69	MEN1 (0.64)	MAPTSMN1; SMN2HTTHPGDKMT2A
	SCHEMBL4491424	0.68	AKR1C3 (0.64)	MAPTSMN1; SMN2ABCG2KMT2AMEN1
	SCHEMBL4482947	0.68	AKR1C3 (0.58)	MAPTSMN1; SMN2HTTHPGDNPC1
	SCHEMBL4496284	0.68	KDM4E (0.53)	MAPTSMN1; SMN2HTTHPGDABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.