Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.39 |
| ▸ | CNR1 | P21554 | 8/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424653 | 0.83 | PDE2A (0.45) | TRPV1 | |
| SCHEMBL14500980 | 0.80 | CDK2 (0.35) | TRPV1DPP4HTR2CCDK1CDK2 | |
| SCHEMBL4494735 | 0.79 | GRM5 (0.35) | CNR2CNR1KCNH2TRPV1GRM5 | |
| SCHEMBL5235784 | 0.79 | TRPV1 (0.38) | CNR2CNR1KCNH2TRPV1GRM5 | |
| SCHEMBL14374398 | 0.79 | GRM5 (0.34) | CNR2CNR1KCNH2TRPV1GRM5 | |
| SCHEMBL5240772 | 0.79 | KDM4E (0.39) | CNR2DPP4GRM5RCE1CDK2 | |
| SCHEMBL5486841 | 0.79 | GRM5 (0.36) | CNR2CNR1KCNH2TRPV1GRM5 | |
| SCHEMBL5236556 | 0.79 | GRM5 (0.38) | CNR2CNR1KCNH2TRPV1GRM5 | |
| SCHEMBL4494732 | 0.78 | TRPV1 (0.35) | CNR2CNR1KCNH2TRPV1GRM5 | |
| SCHEMBL4506761 | 0.78 | GRM5 (0.41) | CNR2CNR1TRPV1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |
| US-20070259893-A1 | microbicides, fungicides; 7-amino-pyrazolo(1,5-a)pyrimidines; controlling unwanted microorganisms | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-11-08 | — | — | US | disclosed |
| US-20050187224-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187224-A1 | Pyrazolopyrimidines | P2RX5, P2RX4, P2RX1 | CNR2 812/4885CNR1 720/4885KCNH2 244/4885 |
| US-20070259893-A1 | microbicides, fungicides; 7-amino-pyrazolo(1,5-a)pyrimidines; controlling unwanted microorganisms | PNPO, CYP4X1, CYP1B1 | CNR2 2192/4885CNR1 1226/4885KCNH2 1929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.