Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424814 | 0.91 | PDE2A (0.46) | PDE2AMEN1GAAKMT2ALMNA | |
| SCHEMBL3429527 | 0.88 | PDE2A (0.42) | PDE2AMEN1GAAKMT2ALMNA | |
| SCHEMBL3423833 | 0.87 | EGLN2 (0.42) | PDE2AMEN1GAAKMT2ALMNA | |
| SCHEMBL8917364 | 0.85 | LMNA (0.44) | PDE2AMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL4494555 | 0.83 | CNR2 (0.39) | TRPV1 | |
| SCHEMBL4817440 | 0.83 | MAPT (0.43) | MEN1GAAKMT2ALMNAALDH1A1 | |
| SCHEMBL4817257 | 0.83 | ALDH1A1 (0.41) | PDE2AGAALMNAALDH1A1TSHR | |
| SCHEMBL81282 | 0.83 | TSHR (0.41) | PDE2AGAAKMT2ALMNAALDH1A1 | |
| SCHEMBL5593378 | 0.82 | PDE2A (0.42) | PDE2AMEN1GAAKMT2ALMNA | |
| SCHEMBL5593427 | 0.81 | ALDH1A1 (0.41) | PDE2AGAAKMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763622-B2 | Substituted 6-(2-halogennphenyl)-triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2010-07-27 | — | — | US | disclosed |
| CN-100537572-C | 6- (2-halophenyl) -triazolopyrimidine derivatives and their use as fungicides | BASF AG (DE) | 2009-09-09 | — | — | CN | disclosed |
| US-20060241128-A1 | Substituted 6-(2-halogennphenyl)-triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2006-10-26 | — | — | US | disclosed |
| CN-1751045-A | 6-(2-halogenphenyl)-triazolopyrimidines derivatives and their use as fungicide | BASF AG (DE) | 2006-03-22 | — | — | CN | disclosed |
| EP-1562948-A2 | 6-(2-HALOGENPHENYL)-TRIAZOLOPYRIMIDINES DERIVATIVES AND THEIR USE AS FUNGICIDE | BASF Aktiengesellschaft (DE) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004041824-A2 | 6-(2-HALOGENPHENYL)-TRIAZOLOPYRIMIDINES DERIVATIVES AND THEIR USE AS FUNGICIDE | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241128-A1 | Substituted 6-(2-halogennphenyl)-triazolopyrimidines | CBR3, CBR1, DCXR | PDE2A 3929/4885MEN1 4790/4885GAA 2774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.