Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 1/20 | 0.47 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3589584 | 0.81 | PPARG (0.47) | CPT1ACPT1BPTGDR2FFAR1 | |
| SCHEMBL4516754 | 0.78 | SRD5A2 (0.50) | CPT1ACPT1BPTGDR2FFAR1SRD5A2 | |
| SCHEMBL4525574 | 0.74 | PTGDR2 (0.56) | PTGDR2FFAR1P2RX3SRD5A2 | |
| SCHEMBL8969156 | 0.74 | SRD5A2 (0.70) | FFAR1SRD5A2 | |
| SCHEMBL3574981 | 0.73 | PPARG (0.46) | PTGDR2FFAR1 | |
| SCHEMBL3587335 | 0.73 | KDM4E (0.46) | PTGDR2FFAR1 | |
| SCHEMBL3576162 | 0.72 | LTB4R (0.48) | PTGDR2FFAR1 | |
| SCHEMBL9036833 | 0.72 | FFAR1 (0.74) | PTGDR2FFAR1PTGDR | |
| SCHEMBL1421946 | 0.71 | PPARG (0.61) | PTGDR2FFAR1P2RX3SRD5A2FAAH | |
| SCHEMBL4522014 | 0.70 | FFAR1 (0.50) | PTGDR2FFAR1SRD5A2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622491-B2 | Type 2 diabetes, atherosclerosis, cardiovascular disease, Syndrome X; carboxylic acids with dialkyldiether or thioether linking groups e.g. {4-[3-(2-Benzotriazol-2-yl-4-chloro-phenoxy)-propoxy]-phenyl}-acetic acid and {4-[3-(2-benzotriazol-2-yl-4-thiophen-2-yl-phenoxy)-propoxy]-phenyl}-acetic acid | METABOLEX INC. (US) | 2009-11-24 | — | — | US | disclosed |