Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34628 | 0.77 | HSD11B1 (0.31) | — | |
| SCHEMBL887992 | 0.77 | — | — | |
| SCHEMBL531260 | 0.73 | LMNA (0.31) | LMNA | |
| SCHEMBL16804589 | 0.70 | — | — | |
| SCHEMBL29143569 | 0.68 | KDM4E (0.31) | KDM4ELMNACYP2C19 | |
| SCHEMBL7639189 | 0.68 | — | — | |
| SCHEMBL18287715 | 0.67 | — | — | |
| Butyrolactone SCHEMBL8984027 | 0.66 | CA1 (0.42) | LMNA | |
| SCHEMBL13917985 | 0.65 | KDM4E (0.32) | KDM4ELMNACYP2C19 | |
| SCHEMBL19663105 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504524-B2 | Method for synthesis of 2,5-dioxane-1,4-diones | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2009-03-17 | — | — | US | disclosed |
| US-7504524-B2 | Method for synthesis of 2,5-dioxane-1,4-diones | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2009-03-17 | — | — | US | disclosed |
| US-7504524-B2 | Method for synthesis of 2,5-dioxane-1,4-diones | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2009-03-17 | — | — | US | disclosed |
| US-20080004453-A1 | Method for Synthesis of 2,5-Dioxane-1,4-Diones | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2008-01-03 | — | — | US | disclosed |
| US-20080004453-A1 | Method for Synthesis of 2,5-Dioxane-1,4-Diones | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2008-01-03 | — | — | US | disclosed |
| US-20080004453-A1 | Method for Synthesis of 2,5-Dioxane-1,4-Diones | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2008-01-03 | — | — | US | disclosed |
| EP-1773803-A1 | METHOD FOR THE SYNTHESIS OF 2,5-DIOXANE-1,4-DIONES | Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S) SAS (FR) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006018524-A1 | METHOD FOR THE SYNTHESIS OF 2,5-DIOXANE-1,4-DIONES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004453-A1 | Method for Synthesis of 2,5-Dioxane-1,4-Diones | CBR3, CBR1, CYP2W1 | KDM4E 1336/4885LMNA 1688/4885CYP2C19 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.