Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437984 | 0.80 | CYP1A2 (0.39) | TAAR1TSHRESR2NPC1TP53 | |
| SCHEMBL5788933 | 0.76 | ESR2 (0.38) | ALOX5TAAR1NOTUMTSHRESR2 | |
| SCHEMBL817554 | 0.74 | ALOX5 (0.65) | ALOX5TAAR1NOTUMTSHRESR2 | |
| SCHEMBL31222672 | 0.74 | ALOX5 (0.65) | ALOX5TAAR1NOTUMTSHRESR2 | |
| SCHEMBL2115007 | 0.73 | NPC1 (0.42) | ALOX5TAAR1NOTUMTSHRESR2 | |
| SCHEMBL28601606 | 0.73 | EGLN2 (0.40) | — | |
| SCHEMBL15287170 | 0.72 | TDO2 (0.41) | ALOX5TAAR1NOTUMTSHRESR2 | |
| SCHEMBL5198605 | 0.72 | TAAR1 (0.40) | ALOX5TAAR1TSHRNPC1TP53 | |
| Hydrochloric Acid SCHEMBL31070804 | 0.71 | ALOX5 (0.62) | ALOX5TAAR1NOTUMTSHRESR2 | |
| SCHEMBL29629014 | 0.71 | ALOX5 (0.62) | ALOX5TAAR1NOTUMTSHRESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009116074-A2 | SUBSTITUTED BENZIMIDAZOLES AS CANNABINOID MODULATOR | CADILA HEALTHCARE LIMITED (IN) | 2009-09-24 | — | — | WO | disclosed |