Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 7/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 7/20 | 0.48 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4496907 | 0.79 | KDM4E (0.47) | CARM1PRMT6OPRD1ACHEBACE1 | |
| SCHEMBL4499128 | 0.78 | OPRD1 (0.56) | OPRD1OPRM1OPRK1 | |
| SCHEMBL4499136 | 0.77 | OPRD1 (0.53) | OPRD1OPRM1OPRK1 | |
| SCHEMBL4499743 | 0.76 | CARM1 (0.74) | CARM1PRMT6ACHEBACE1 | |
| SCHEMBL9140636 | 0.74 | OPRD1 (0.56) | OPRD1OPRM1OPRK1 | |
| SCHEMBL4489428 | 0.74 | OPRM1 (0.62) | OPRD1OPRM1OPRK1 | |
| SCHEMBL4489432 | 0.74 | CYP1A2 (0.50) | OPRD1OPRM1OPRK1 | |
| SCHEMBL4497092 | 0.73 | OPRD1 (0.60) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6394117 | 0.73 | OPRD1 (0.58) | OPRD1OPRM1OPRK1 | |
| SCHEMBL4499124 | 0.72 | OPRD1 (0.47) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576105-B2 | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives | JANSSEN PHARMACEUTICA, NV (BE) | 2009-08-18 | — | — | US | disclosed |
| US-20060106066-A1 | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives | BAXTER ELLEN W | 2006-05-18 | — | — | US | disclosed |
| US-20040082612-A1 | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives | JANSSEN PHARMACEUTICALS N.V. (BE) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106066-A1 | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives | OPRD1, OPRK1, OPRM1 | CARM1 1756/4885PRMT6 1096/4885PRMT8 861/4885 |
| US-20040082612-A1 | Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives | OPRD1, OPRK1, OPRM1 | CARM1 1756/4885PRMT6 1096/4885PRMT8 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.