Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.47 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4498398 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDMEN1KMT2ANPC1 | |
| SCHEMBL4506339 | 0.85 | SMN1; SMN2 (0.61) | SCDSMN1; SMN2HPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4518322 | 0.85 | MRGPRX4 (0.46) | SGMS2MRGPRX4GRM4PIM1PIM3 | |
| SCHEMBL4505284 | 0.79 | ALDH1A1 (0.66) | SCDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4493419 | 0.78 | SMN1; SMN2 (0.52) | SCDSMN1; SMN2HPGDSLC12A2SLC12A5 | |
| SCHEMBL4510719 | 0.78 | MRGPRX4 (0.66) | SCDSMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL4507518 | 0.77 | SMN1; SMN2 (0.51) | SCDSMN1; SMN2HPGDSLC12A2SLC12A5 | |
| SCHEMBL4507671 | 0.77 | SMN1; SMN2 (0.58) | SCDSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4503513 | 0.77 | SMN1; SMN2 (0.62) | SCDSMN1; SMN2HPGDSLC12A2SLC12A5 | |
| SCHEMBL23241871 | 0.77 | SMN1; SMN2 (0.50) | SCDSMN1; SMN2HPGDSLC12A2SLC12A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | SCD 1/4885SMN1; SMN2 2075/4885HPGD 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.