Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 17/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2395691 | 0.88 | ALDH1A1 (0.41) | CRHR1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL4496282 | 0.84 | ALDH1A1 (0.46) | CRHR1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL4510042 | 0.82 | CRHR1 (0.50) | CRHR1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL13965584 | 0.74 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL2392414 | 0.73 | ALDH1A1 (0.45) | CRHR1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL5623938 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL2393935 | 0.71 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL3039488 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPT | |
| SCHEMBL4501540 | 0.71 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL4195023 | 0.70 | ALDH1A1 (0.34) | CRHR1ALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023729-A1 | Trisubstituted amine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1979341-A1 | TRISUBSTITUTED AMINE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007088999-A1 | TRISUBSTITUTED AMINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023729-A1 | Trisubstituted amine compound | CETP, MTTP, APOB | CRHR1 3834/4885ALDH1A1 3188/4885KDM4E 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.