Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4497421 | 1.00 | KMT2A (0.49) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL20028731 | 0.85 | MAPT (0.47) | KMT2AKDM4EALDH1A1HTTTDP1 | |
| SCHEMBL4764216 | 0.85 | MAPT (0.47) | KMT2AKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL1504155 | 0.85 | ALDH1A1 (0.44) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL30935351 | 0.85 | ALDH1A1 (0.44) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL13264795 | 0.84 | CA12 (0.51) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL295741 | 0.84 | ALDH1A1 (0.53) | KMT2AKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7056947 | 0.84 | ALDH1A1 (0.53) | KMT2AKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL10391474 | 0.84 | ALDH1A1 (0.53) | KMT2AKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL24643324 | 0.83 | ALOX15 (0.57) | KMT2AKDM4EALDH1A1HTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498431-B2 | Process for the preparation of chiral azetidinones | FRAMROZE BOMI PATEL | 2009-03-03 | — | — | US | disclosed |
| US-7498431-B2 | Process for the preparation of chiral azetidinones | FRAMROZE BOMI PATEL | 2009-03-03 | — | — | US | disclosed |
| US-7498431-B2 | Process for the preparation of chiral azetidinones | FRAMROZE BOMI PATEL | 2009-03-03 | — | — | US | disclosed |
| US-20070129540-A1 | Process for the preparation of chiral azetidinones | OPUS ORGANICS PVT LIMITED (IN) | 2007-06-07 | — | — | US | disclosed |
| US-20070129540-A1 | Process for the preparation of chiral azetidinones | OPUS ORGANICS PVT LIMITED (IN) | 2007-06-07 | — | — | US | disclosed |
| US-20070129540-A1 | Process for the preparation of chiral azetidinones | OPUS ORGANICS PVT LIMITED (IN) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129540-A1 | Process for the preparation of chiral azetidinones | CYP1B1, ALDH7A1, CYP3A5 | KMT2A 4551/4885CA12 3334/4885CA1 3251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.