SCHEMBL44979

SCHEMBL44979

COC(C)Cc1cc(CC(C)OC)cc(C(C)(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 7/20 0.47
TACR1 P25103 1/20 0.35
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
ELANE P08246 1/20 0.31
CD69 Q07108 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45193 0.85 TAAR1 (0.33)
SCHEMBL16014057 0.82 HTR2A (0.47) TACR1TP53TSHRLMNA
SCHEMBL25774449 0.79 HMGCR (0.49) HMGCRTP53TSHRGABRA1GABRB2
SCHEMBL1225023 0.77 HMGCR (0.45) HMGCRTSHRRXRARXRBRXRG
SCHEMBL45261 0.75 HMGCR (0.46) HMGCRTACR1TP53TSHRGABRA1
SCHEMBL6157363 0.75 HMGCR (0.46) HMGCRTP53TSHRGABRA1GABRB2
SCHEMBL10540692 0.75 HMGCR (0.46) HMGCRTACR1TP53TSHRGABRA1
SCHEMBL10271929 0.75 IDO1 (0.32)
SCHEMBL22129162 0.74 HMGCR (0.50) HMGCRTACR1TP53TSHRGABRA1
SCHEMBL9879684 0.74 HMGCR (0.53) HMGCRTP53TSHRGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2284203-B1 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE CO (US) 2015-03-04 EP claimed
US-8575279-B2 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE COMPANY LLC (US) 2013-11-05 US claimed
US-20130150539-A1 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-06-13 US claimed
EP-1781715-B1 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS CHEVRON ORONITE CO (US) 2011-05-18 EP claimed
EP-2284203-A2 Method for preparation of polyolefins containing exo-olefin chain ends Chevron Oronite Company LLC (US) 2011-02-16 EP claimed
US-20100311915-A1 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS CHEVRON ORONITE COMPANY LLC 2010-12-09 US claimed
US-7709580-B2 quenching cationic quasi-living polyolefin polymer system with pyrroles, imidazoles; lubricating oil additives CHEVRON ORONITE COMPANY LLC (US) 2010-05-04 US claimed
US-7420019-B2 Quenching a cationic quasi-living polyolefin polymer system with one or more hindered secondary or tertiary amines CHEVRON ORONITE COMPANY LLC (US) 2008-09-02 US claimed
US-20060041084-A1 Quenching a cationic quasi-living polyolefin polymer system with one or more hindered secondary or tertiary amines CHEVRON ORONITE COMPANY LLC 2006-02-23 US claimed
US-20060041083-A1 quenching cationic quasi-living polyolefin polymer system with pyrroles, imidazoles; lubricating oil additives CHEVRON ORONITE COMPANY LLC 2006-02-23 US claimed
EP-3774975-B1 POLY(ETHER-CARBONATE)-BASED POLYMERS AND MEDICAL DEVICES MEDTRONIC INC (US) 2023-06-14 EP disclosed
US-11491338-B2 Polymeric feed-thru for chronic implantable devices CARDIAC PACEMAKERS, INC. (US) 2022-11-08 US disclosed
CN-111902448-B Poly (ether-carbonate) -based polymer and medical device 美敦力公司 2022-09-30 CN disclosed
US-11274181-B2 Polyimide dispersants and methods of making and using thereof CHEVRON ORONITE COMPANY LLC (US) 2022-03-15 US disclosed
EP-3774975-A1 POLY(ETHER-CARBONATE)-BASED POLYMERS AND MEDICAL DEVICES Medtronic, Inc. (US) 2021-02-17 EP disclosed
US-20060041084-A1 Quenching a cationic quasi-living polyolefin polymer system with one or more hindered secondary or tertiary amines CHEVRON ORONITE COMPANY LLC 2006-02-23 US disclosed
EP-0795182-B1 ION-CONDUCTIVE POLYMERS DANACELL APS (DK) 1999-03-03 EP disclosed
US-5789106-A Ion-conductive polymers DANACELL APS (DK) 1998-08-04 US disclosed
EP-0795182-A1 ION-CONDUCTIVE POLYMERS DANACELL APS (DK) 1997-09-17 EP disclosed
WO-1996017359-A1 ION-CONDUCTIVE POLYMERS DANACELL APS (DK) 1996-06-06 WO disclosed