Sugi Predict

Sugi Predict / Compounds / SCHEMBL45193

SCHEMBL45193

SCHEMBL45193

COC(C)Cc1cc(CC(C)OC)cc(CC(C)OC)c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TAAR1 Q96RJ0 4/20 0.33
▸ ALOX15 P16050 1/20 0.32
▸ ALOX12 P18054 1/20 0.32
▸ FOS P01100 1/20 0.32
▸ TTR P02766 1/20 0.32
▸ JUN P05412 1/20 0.32
▸ NR3C1 P04150 1/20 0.32
▸ HSD17B1 P14061 1/20 0.32
▸ HSD17B2 P37059 1/20 0.32
▸ SLC6A4 P31645 2/20 0.32
▸ SLC6A2 P23975 2/20 0.32
▸ MAOA P21397 1/20 0.32
▸ SLC6A3 Q01959 1/20 0.32
▸ SIGMAR1 Q99720 1/20 0.32
▸ CYP2A6 P11509 1/20 0.32
▸ ADORA2A P29274 1/20 0.32
▸ ADORA1 P30542 1/20 0.32
▸ LDHA P00338 1/20 0.31
▸ HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10271929 0.89 IDO1 (0.32) —
SCHEMBL44955 0.85 TAAR1 (0.50) TAAR1SLC6A4SLC6A2MAOASLC6A3
SCHEMBL44979 0.85 HMGCR (0.47) —
SCHEMBL11514104 0.84 TAAR1 (0.32) TAAR1SLC6A4SLC6A2MAOASLC6A3
SCHEMBL43314 0.83 SLC6A4 (0.46) TAAR1SLC6A4SLC6A2MAOASLC6A3
SCHEMBL13006663 0.79 SIGMAR1 (0.56) TAAR1SLC6A4SLC6A2MAOASLC6A3
SCHEMBL13189946 0.79 SIGMAR1 (0.56) TAAR1SLC6A4SLC6A2MAOASLC6A3
SCHEMBL2555409 0.79 SIGMAR1 (0.56) TAAR1SLC6A4SLC6A2MAOASLC6A3
SCHEMBL16213676 0.77 TAAR1 (0.43) TAAR1SLC6A4SLC6A2MAOASLC6A3
SCHEMBL28334721 0.76 ALOX15 (0.32) TAAR1ALOX15ALOX12FOSTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795247-B2 Polyolefin dispersants and methods of making and using thereof THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-10-24 — — US claimed
US-20210189030-A1 Polyolefin Dispersants and Methods of Making and Using Thereof UNIVERSITY OF SOUTHERN MISSISSIPPI 2021-06-24 — — US claimed
EP-3684842-A1 POLYOLEFIN DISPERSANTS AND METHODS OF MAKING AND USING THEREOF Chevron Oronite Company LLC (US) 2020-07-29 — — EP claimed
US-20190284314-A1 Polyolefin Dispersants and Methods of Making and Using Thereof CHEVRON ORONITE COMPANY LLC. 2019-09-19 — — US claimed
WO-2019055978-A1 POLYOLEFIN DISPERSANTS AND METHODS OF MAKING AND USING THEREOF CHEVRON ORONITE COMPANY LLC (US) 2019-03-21 — — WO claimed
EP-2387592-B1 FUNCTIONALIZATION OF POLYOLEFINS WITH PHENOXY DERIVATIVES THE UNIV OF SOUTHERN MISSISSIPPI (US) 2018-08-29 — — EP claimed
US-9650449-B2 Functionalization of polyolefins with phenoxy derivatives THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2017-05-16 — — US claimed
EP-2459599-B1 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS UNIV SOUTHERN MISSISSIPPI (US) 2016-07-20 — — EP claimed
US-20130281742-A1 METHOD AND SYNTHESIS OF INITIATORS FOR TELECHELIC POLYISOBUTYLENES THE UNIVERSITY OF AKRON (US) 2013-10-24 — — US claimed
US-20130131280-A1 FUNCTIONALIZATION OF POLYOLEFINS WITH PHENOXY DERIVATIVES THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-05-23 — — US claimed
US-5473029-A Copolymerization of isobutylene with a conjugated diolefin bearing an allylic halide in the presence of an initiator and a lewis acid BAYER RUBBER INC. (CA) 1995-12-05 — — US claimed
EP-0609737-A2 Process for producing a halogenated butyl rubber BAYER RUBBER INC. (CA) 1994-08-10 — — EP claimed
US-RE34640-E Polymerizing isobutylene, adding monomer to make block polymer; metal halide, initiator and electron pair doner solvent UNIVERSITY OF AKRON (US) 1994-06-14 — — US claimed
EP-0341012-B1 UNIFORM MOLECULAR WEIGHT POLYMERS EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1992-12-30 — — EP claimed
WO-1991011468-A1 NEW THERMOPLASTIC ELASTOMERS THE UNIVERSITY OF AKRON (US) 1991-08-08 — — WO claimed
WO-1990010657-A1 POLYURETHANE FOAM THE UNIVERSITY OF AKRON (US) 1990-09-20 — — WO claimed
US-4946899-A CARBOCATIONIC POLYMERIZATION INVOLVING HOMOPOLYMERIZATION OF ELASTOMER FOLLOWED BY COPOLYMERIZATION TO ADD GLASSY SEGMENTS; FORMING LIVING POLYMERS WITH A METAL HALIDE, PROMOTER AND SOLVENT MIXTURE THE UNIVERSITY OF AKRON (US) 1990-08-07 — — US claimed
US-4939184-A DIOL IS HYDROXY ENDCAPPED POLYISOBUTYLENE UNIVERSITY OF AKRON (US) 1990-07-03 — — US claimed
EP-0346919-A2 Improved thermoplastic elastomers EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1989-12-20 — — EP claimed
EP-0341012-A2 Uniform molecular weight polymers EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1989-11-08 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281742-A1 METHOD AND SYNTHESIS OF INITIATORS FOR TELECHELIC POLYISOBUTYLENES TET1, TET3, DNMT1 TAAR1 282/4885ALOX15 1370/4885ALOX12 1499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.