SCHEMBL45261

SCHEMBL45261

CC(Cl)Cc1cc(CC(C)Cl)cc(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 6/20 0.46
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
HTR1D P28221 1/20 0.32
POLB P06746 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
CYP2C19 P33261 1/20 0.31
TACR1 P25103 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7764667 0.96 HMGCR (0.50) HMGCRTP53TSHRGABRA1GABRB2
SCHEMBL3683050 0.88 HMGCR (0.39) HMGCRTP53TSHR
SCHEMBL45291 0.83 PNMT (0.33) TP53POLBHTR2AHTR2BCYP2C19
SCHEMBL25774449 0.82 HMGCR (0.49) HMGCRTP53TSHRGABRA1GABRB2
SCHEMBL4445053 0.80 HTR2A (0.50) TP53TSHRHTR2AHTR2CHTR2B
SCHEMBL10540692 0.78 HMGCR (0.46) HMGCRTP53TSHRGABRA1GABRB2
SCHEMBL6157363 0.78 HMGCR (0.46) HMGCRTP53TSHRGABRA1GABRB2
SCHEMBL9879684 0.77 HMGCR (0.53) HMGCRTP53TSHRGABRA1GABRB2
SCHEMBL2332071 0.77 HTR2A (0.46) TP53TSHRRXRARXRBRXRG
SCHEMBL44979 0.75 HMGCR (0.47) HMGCRTP53TSHRGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795247-B2 Polyolefin dispersants and methods of making and using thereof THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-10-24 US claimed
US-20210189030-A1 Polyolefin Dispersants and Methods of Making and Using Thereof UNIVERSITY OF SOUTHERN MISSISSIPPI 2021-06-24 US claimed
US-20190284314-A1 Polyolefin Dispersants and Methods of Making and Using Thereof CHEVRON ORONITE COMPANY LLC. 2019-09-19 US claimed
EP-2459599-B1 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS UNIV SOUTHERN MISSISSIPPI (US) 2016-07-20 EP claimed
EP-2284203-B1 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE CO (US) 2015-03-04 EP claimed
US-8895672-B2 Production of vinylidene-terminated and sulfide-terminated telechelic polyolefins via quenching with disulfides CHEVRON ORONITE COMPANY LLC (US) 2014-11-25 US claimed
US-20130331525-A1 PRODUCTION OF VINYLIDENE-TERMINATED AND SULFIDE-TERMINATED TELECHELIC POLYOLEFINS VIA QUENCHING WITH DISULFIDES CHEVRON ORONITE COMPANY LLC (US) 2013-12-12 US claimed
US-8575279-B2 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE COMPANY LLC (US) 2013-11-05 US claimed
US-8507641-B2 Production of vinylidene-terminated and sulfide-terminated telechelic polyolefins via quenching with disulfides CHEVRON ORONITE COMPANY LLC (US) 2013-08-13 US claimed
US-20130158207-A1 PRODUCTION OF VINYLIDENE-TERMINATED AND SULFIDE-TERMINATED TELECHELIC POLYOLEFINS VIA QUENCHING WITH DISULFIDES CHEVRON ORONITE COMPANY LLC (US) 2013-06-20 US claimed
US-6939933-B2 Heat exchanging capacity EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-09-06 US claimed
EP-1237950-B1 PRODUCTION OF ISOBUTYLENE COPOLYMERS EXXONMOBIL CHEM PATENTS INC (US) 2005-05-04 EP claimed
US-20040054103-A1 Process for polymerizing cationically polymerizable monomers WEBB ROBERT N (US) 2004-03-18 US claimed
EP-1358230-A1 PROCESS FOR POLYMERIZING CATIONICALLY POLYMERIZABLE MONOMERS ExxonMobil Chemical Patents Inc. (US) 2003-11-05 EP claimed
US-6620898-B2 In the presence of a catalyst composition of a lewis acid based on a metal and an initiator alkyl, alkenyl or aryl substituted with a carboxy, halo, hydroxy or alkoxy EXXONMOBIL CHEMICAL PATENTS INC. 2003-09-16 US claimed
US-20020173612-A1 Production of polyisobutylene copolymers WEBB ROBERT N (US) 2002-11-21 US claimed
EP-1237950-A1 PRODUCTION OF ISOBUTYLENE COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 2002-09-11 EP claimed
US-6444768-B1 CONTINUOUS SLURRYING POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. 2002-09-03 US claimed
WO-2002050141-A1 PROCESS FOR POLYMERIZING CATIONICALLY POLYMERIZABLE MONOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-06-27 WO claimed
WO-2001036498-A1 PRODUCTION OF ISOBUTYLENE COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO claimed