SCHEMBL449799

SCHEMBL449799

C=CC(=O)OC(C)OCCOc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.61
ALDH1A1 P00352 2/20 0.48
PKM P14618 2/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
RAB9A P51151 2/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 1/20 0.43
PARP10 Q53GL7 1/20 0.42
PTGER4 P35408 1/20 0.42
PTGER2 P43116 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
MTNR1A P48039 2/20 0.41
MTNR1B P49286 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
TEAD1 P28347 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL29231472 0.95 THRB (0.56) THRBALDH1A1PKMMEN1KMT2A
SCHEMBL10836550 0.93 THRB (0.57) THRBALDH1A1PKMMEN1KMT2A
SCHEMBL18426495 0.92 THRB (0.56) THRBALDH1A1PKMMEN1KMT2A
SCHEMBL28932859 0.92 THRB (0.52) THRBALDH1A1PKMMAPTSMN1; SMN2
SCHEMBL29217059 0.91 THRB (0.52) THRBALDH1A1PKMMEN1KMT2A
SCHEMBL11123924 0.87 THRB (0.68) THRBALDH1A1PKMMEN1KMT2A
SCHEMBL28230344 0.84 THRB (0.72) THRBALDH1A1PKMMEN1KMT2A
SCHEMBL16240775 0.83 KDM4E (0.50) ALDH1A1PKMMEN1KMT2AMAPT
SCHEMBL8769134 0.82 MTNR1A (0.49) THRBALDH1A1PKMMEN1KMT2A
SCHEMBL28507336 0.81 THRB (0.64) THRBALDH1A1PKMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 594 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250389633-A1 SYNTHETIC HUMAN CELL MIMIC PARTICLE FOR CYTOMETRIC OR COULTER DEVICE SLINGSHOT BIOSCIENCES, INC. (US) 2025-12-25 US claimed
US-20250298042-A1 ENGINEERED PARTICLES AS RED BLOOD CELL MIMICS AND COMPOSITIONS CONTAINING SAME FOR HEMATOLOGY SLINGSHOT BIOSCIENCES, INC. (US) 2025-09-25 US claimed
EP-4608872-A2 SIZE-TUNABLE SYNTHETIC PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME FOR IMMUNE CELL ACTIVATION Slingshot Biosciences, Inc. (US) 2025-09-03 EP claimed
US-12379387-B2 Engineered particles as red blood cell mimics and compositions containing same for hematology SLINGSHOT BIOSCIENCES, INC. (US) 2025-08-05 US claimed
EP-3256850-B1 HYDROGEL PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME SLINGSHOT BIOSCIENCES INC (US) 2025-07-09 EP claimed
US-12352679-B2 Synthetic human cell mimic particle for cytometric or coulter device SLINGSHOT BIOSCIENCES, INC. (US) 2025-07-08 US claimed
EP-4577823-A2 COMPOSITIONS AND METHODS FOR SINGLE WELL MULTIPLEXED CALIBRATION AND COMPENSATION Slingshot Biosciences, Inc. (US) 2025-07-02 EP claimed
US-20250189428-A1 COMPOSITIONS AND METHODS FOR SINGLE WELL MULTIPLEXED CALIBRATION AND COMPENSATION SLINGSHOT BIOSCIENCES, INC. (US) 2025-06-12 US claimed
US-12312595-B2 Hydrogel particles as feeder cells and as synthetic antigen presenting cells SLINGSHOT BIOSCIENCES, INC. (US) 2025-05-27 US claimed
US-20250164373-A1 SYNTHETIC HUMAN CELL MIMIC PARTICLE FOR CYTOMETRIC OR COULTER DEVICE SLINGSHOT BIOSCIENCES, INC. (US) 2025-05-22 US claimed
US-20020042483-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-04-11 US claimed
US-20020037984-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-03-28 US claimed
EP-0735062-B1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO (JP) 2002-01-30 EP claimed
US-6329485-B1 FOR INTRAOCULAR LENSES BAUSCH & LOMB INCORPORATED 2001-12-11 US claimed
US-6206550-B1 BACKLIGHT WITH LENS PORTION MADE FROM A CURABLE COMPOSITION WHICH INCLUDES A BIS(4-(METH)ACRYLOYL-THIOPHENYL) SULFIDE AND (METH)ACRYLATES; HIGH BRIGHTNESS-ENHANCING EFFECT ON LENSES OF PROJECTION TVS AND STEREOSCOPIC PHOTOGRAPHY. MITSUBISHI RAYON COMPANY LTD. (JP) 2001-03-27 US claimed
US-6110561-A Break-resistant multiribbed plate of polymethyl methacrylate ROEHM GMBH CHEMISCHE FABRIK (DE) 2000-08-29 US claimed
WO-2000034804-A1 HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-06-15 WO claimed
US-5969867-A ACRYLIC ESTERS MITSUBISHI RAYON COMPANY LTD. (JP) 1999-10-19 US claimed
EP-0735062-A1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO., LTD. (JP) 1996-10-02 EP claimed
US-4789620-A CROSSLINKED, CURED COATING MITSUBISHI RAYON CO. LTD. (JP) 1988-12-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250389633-A1 SYNTHETIC HUMAN CELL MIMIC PARTICLE FOR CYTOMETRIC OR COULTER DEVICE CD4, ICOS, CD69 THRB 502/4885ALDH1A1 3752/4885PKM 949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.