Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | GAA | P10253 | 2/20 | 0.77 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.77 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.77 |
| ▸ | UTRN | P46939 | 4/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | AHR | P35869 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 9/20 | 0.66 |
| ▸ | NPC1 | O15118 | 8/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2243039 | 0.86 | UTRN (0.77) | SMN1; SMN2KDM4EKMT2AGAACACNA1B | |
| SCHEMBL2245400 | 0.85 | UTRN (0.69) | SMN1; SMN2KDM4EKMT2AGAACACNA1B | |
| SCHEMBL2245790 | 0.84 | UTRN (0.77) | SMN1; SMN2KDM4EKMT2AGAACACNA1B | |
| SCHEMBL4510499 | 0.82 | UTRN (0.65) | SMN1; SMN2KDM4EKMT2AGAACACNA1B | |
| Ezutromid SCHEMBL29376738 | 0.81 | UTRN (1.00) | SMN1; SMN2KDM4EKMT2AGAACACNA1B | |
| Ezutromid SCHEMBL30791155 | 0.81 | UTRN (1.00) | SMN1; SMN2KDM4EKMT2AGAACACNA1B | |
| Ezutromid SCHEMBL732212 | 0.81 | UTRN (1.00) | SMN1; SMN2KDM4EKMT2AGAACACNA1B | |
| Ezutromid SCHEMBL31080435 | 0.81 | UTRN (1.00) | SMN1; SMN2KDM4EKMT2AGAACACNA1B | |
| SCHEMBL26686966 | 0.81 | UTRN (0.67) | SMN1; SMN2KDM4EKMT2AGAACACNA1B | |
| SCHEMBL2243160 | 0.81 | UTRN (0.72) | SMN1; SMN2KDM4EKMT2AGAACACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-10-15 | — | — | US | disclosed |
| EP-1933834-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007042816-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | IL4I1, EPX, IL4 | SMN1; SMN2 2389/4885KDM4E 1264/4885KMT2A 4004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.