Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TTR | P02766 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | DBH | P09172 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885118 | 0.85 | HSD17B10 (0.55) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL9293760 | 0.80 | ALDH1A1 (0.41) | HSD17B10TSHRCYP3A4RECQLALDH1A1 | |
| SCHEMBL2415959 | 0.80 | HSD17B10 (0.50) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL10971449 | 0.78 | IGF1R (0.46) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL2927011 | 0.78 | HSD17B10 (0.48) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL15517328 | 0.78 | PNMT (0.32) | — | |
| SCHEMBL15517336 | 0.76 | PNMT (0.31) | CYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL445337 | 0.76 | HSD17B10 (0.46) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL1469394 | 0.76 | TAAR1 (0.56) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL6809958 | 0.76 | HSD17B10 (0.46) | HSD17B10TSHRCYP3A4TTRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318429-A1 | Compounds, Compositions and Methods Comprising Heteroaromatic Derivatives | INSTITUTE FOR ONEWORLD HEALTH | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318429-A1 | Compounds, Compositions and Methods Comprising Heteroaromatic Derivatives | CFTR, PKD1, PKD2 | HSD17B10 1275/4885TSHR 2802/4885CYP3A4 1541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.