SCHEMBL449860

SCHEMBL449860

C=C(C#N)C(=O)OCCC(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
TSHR P16473 1/20 0.53
SLC13A3 Q8WWT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4579700 0.82 TSHR (0.68) ALDH1A1TSHR
SCHEMBL10452959 0.82 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL13322898 0.81 TSHR (0.58) ALDH1A1TSHR
SCHEMBL447489 0.81 ALDH1A1 (0.57) ALDH1A1TSHR
SCHEMBL10393820 0.81 ALDH1A1 (0.49) ALDH1A1TSHR
SCHEMBL12220307 0.80 TSHR (0.56) ALDH1A1TSHR
SCHEMBL5404500 0.79 ALDH1A1 (0.59) ALDH1A1TSHR
SCHEMBL4580407 0.78 TSHR (0.63) ALDH1A1TSHR
SCHEMBL4578754 0.78 TSHR (0.63) ALDH1A1TSHR
SCHEMBL1982870 0.76 TSHR (0.61) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111615666-B Method for producing planar polymer stacks 阿科玛法国公司 2024-02-06 CN claimed
EP-3714328-A1 METHOD FOR PRODUCING A PLANAR POLYMERIC STACK Arkema France (FR) 2020-09-30 EP claimed
CN-111615666-A Method for producing a planar polymer stack 阿科玛法国公司 2020-09-01 CN claimed
CN-111615666-B Method for producing planar polymer stacks 阿科玛法国公司 2024-02-06 CN disclosed
US-11454880-B2 Method for producing a planar polymer stack ARKEMA FRANCE (FR) 2022-09-27 US disclosed
US-20200379339-A1 METHOD FOR PRODUCING A PLANAR POLYMER STACK ARKEMA FRANCE (FR) 2020-12-03 US disclosed
EP-3714328-A1 METHOD FOR PRODUCING A PLANAR POLYMERIC STACK Arkema France (FR) 2020-09-30 EP disclosed
CN-111615666-A Method for producing a planar polymer stack 阿科玛法国公司 2020-09-01 CN disclosed
EP-2614096-B1 ADHESIVE SYSTEM, METHOD OF ASSEMBLY OF DISTINCT COMPONENTS THEREWITH TEKNOR APEX CO (US) 2018-12-05 EP disclosed
US-8871864-B2 Adhesive system, method of assembly of distinct components therewith TEKNOR APEX COMPANY (US) 2014-10-28 US disclosed
EP-2614096-A1 ADHESIVE SYSTEM, METHOD OF ASSEMBLY OF DISTINCT COMPONENTS THEREWITH Teknor Apex Company (US) 2013-07-17 EP disclosed
US-20120064356-A1 Adhesive system, method of assembly of distinct components therewith TEKNOR APEX COMPANY (US) 2012-03-15 US disclosed
WO-2012033520-A1 ADHESIVE SYSTEM, METHOD OF ASSEMBLY OF DISTINCT COMPONENTS THEREWITH TEKNOR APEX COMPANY (US) 2012-03-15 WO disclosed
US-6583250-B2 Particularly to cyanoacrylate adhesives, by mixing in a polymerization initiator capable of initiating polymerization of the monomers of the adhesive, at a temperature above the polyolefin's glass transition temperature HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-06-24 US disclosed
US-20010009954-A1 POLYOLEFINE MATERIALS WITH IMPROVED ADHESIVITY COGNIS DEUTSCHLAND GMBH & CO. KG (DE) 2001-07-26 US disclosed