Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.77 |
| ▸ | BCHE | P06276 | 4/20 | 0.77 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252897 | 0.93 | ACHE (0.67) | ACHEBCHEHTR1ASLC6A4 | |
| SCHEMBL9253392 | 0.92 | ACHE (0.65) | ACHEBCHEHTR1ASLC6A4 | |
| SCHEMBL9254685 | 0.89 | ACHE (0.60) | ACHEBCHEHTR1ASLC6A4 | |
| Fumaric Acid SCHEMBL9254339 | 0.88 | ACHE (0.60) | ACHEBCHEHTR1ASLC6A4 | |
| Fumaric Acid SCHEMBL9254343 | 0.88 | ACHE (0.60) | ACHEBCHEHTR1ASLC6A4 | |
| SCHEMBL9246613 | 0.88 | HTR2A (0.59) | ACHEBCHE | |
| Fumaric Acid SCHEMBL9249220 | 0.88 | ACHE (0.59) | ACHEBCHEHTR1ASLC6A4 | |
| Fumaric Acid SCHEMBL9249239 | 0.88 | ACHE (0.59) | ACHEBCHEHTR1ASLC6A4 | |
| SCHEMBL25244154 | 0.84 | ACHE (0.83) | ACHEBCHE | |
| SCHEMBL9250309 | 0.84 | ACHE (0.83) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252814-B2 | Agents and crystals for improving excretory potency of urinary bladder | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-08-28 | — | — | US | disclosed |
| US-20090264467-A1 | Agents and crystals for improving excretory potency of urinary bladder | ISHIHARA YUJI | 2009-10-22 | — | — | US | disclosed |
| EP-1891954-A2 | Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder | Takeda Pharmaceutical Company Limited (JP) | 2008-02-27 | — | — | EP | disclosed |
| US-20060281725-A1 | Agents and crystals for improving excretory potency of urinary bladder | ISIHARA YUJI | 2006-12-14 | — | — | US | disclosed |
| EP-1604653-A1 | Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder | Takeda Pharmaceutical Company Limited (JP) | 2005-12-14 | — | — | EP | disclosed |
| US-20040116457-A1 | Agents for improving excretory potency of urinary bladder | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-17 | — | — | US | disclosed |
| US-20020177593-A1 | Agents and crystals for improving excretory potency of urinary bladder | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2002-11-28 | — | — | US | disclosed |
| EP-1118322-A1 | DRUGS FOR IMPROVING VESICAL EXCRETORY STRENGTH | Takeda Chemical Industries, Ltd. (JP) | 2001-07-25 | — | — | EP | disclosed |
| EP-0664291-B1 | PYRIMIDINE COMPOUND | UBE INDUSTRIES (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5610303-A | MONOAMIDE OXIDASE INHIBITORS | UBE INDUSTRIES, LTD. (JP) | 1997-03-11 | — | — | US | disclosed |
| US-5441967-A | Treating cerebral edema; anticholinesterase or brain function-improving agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-15 | — | — | US | disclosed |
| EP-0664291-A1 | PYRIMIDINE COMPOUND | UBE INDUSTRIES, LTD. (JP) | 1995-07-26 | — | — | EP | disclosed |
| CN-1088207-A | pyrimidine compounds | UBE INDUSTRIES (JP) | 1994-06-22 | — | — | CN | disclosed |
| CN-1024548-C | Cyclic amine compounds and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-05-18 | — | — | CN | disclosed |
| US-5294625-A | 1-benzyl,4-((4-dialkylaminophenyl)carbonyl)piperidines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0378207-B1 | CYCLIC AMINE COMPOUNDS AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-5177087-A | Cerebral edema, cholinesterase inhibitor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| CN-1053231-A | Cyclic amine compound and uses thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-07-24 | — | — | CN | disclosed |
| EP-0378207-A1 | Cyclic amine compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264467-A1 | Agents and crystals for improving excretory potency of urinary bladder | ACHE, BCHE, PDE7A | ACHE 1/4885BCHE 2/4885HTR1A 2390/4885 |
| US-20020177593-A1 | Agents and crystals for improving excretory potency of urinary bladder | ACHE, BPHL, BCHE | ACHE 1/4885BCHE 3/4885HTR1A 3634/4885 |
| US-20060281725-A1 | Agents and crystals for improving excretory potency of urinary bladder | ACHE, BCHE, PDE7A | ACHE 1/4885BCHE 2/4885HTR1A 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.