Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.63 |
| ▸ | RXRB | P28702 | 2/20 | 0.63 |
| ▸ | RXRG | P48443 | 2/20 | 0.63 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766205 | 0.86 | CYP4F2 (0.56) | NR4A2KDM4CCYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL4500448 | 0.84 | NR4A2 (0.61) | NR4A2MAOBMAOACYP4F2CYP4A11 | |
| SCHEMBL4508058 | 0.84 | MAOB (0.51) | RXRARXRBRXRGNR4A2MAOB | |
| SCHEMBL4505531 | 0.81 | MRGPRX4 (0.67) | NR4A2MAOBCYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL4491985 | 0.78 | MRGPRX4 (0.62) | NPC1RAB9AKDM4CCYP4F2CYP4A11 | |
| SCHEMBL8106373 | 0.78 | RXRA (0.66) | RXRARXRBRXRGNR4A2MAOB | |
| SCHEMBL694229 | 0.77 | RXRA (1.00) | RXRARXRBRXRGNR4A2MAOB | |
| SCHEMBL11617562 | 0.77 | P4HTM (0.60) | NR4A2MAOBCYP1A2CYP2C9KDM4C | |
| SCHEMBL4492876 | 0.77 | MAPT (0.52) | RXRARXRBRXRGNR4A2MAOB | |
| SCHEMBL4510719 | 0.77 | MRGPRX4 (0.66) | RXRARXRBNPC1RAB9AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | RXRA 2808/4885RXRB 1875/4885RXRG 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.