Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.61 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565095 | 0.87 | ESR1 (0.43) | ESR1ESR2PDCD1CD274ALDH1A1 | |
| SCHEMBL10533396 | 0.84 | ESR1 (0.46) | ESR1ESR2PDCD1CD274ALDH1A1 | |
| SCHEMBL955060 | 0.80 | TYR (0.41) | ESR1ESR2ALDH1A1CYP2C9LMNA | |
| SCHEMBL9428117 | 0.80 | ESR1 (0.46) | ESR1ESR2PDCD1CD274ALDH1A1 | |
| SCHEMBL958687 | 0.78 | ALDH1A1 (0.44) | ESR1ESR2ALDH1A1ACHELMNA | |
| SCHEMBL10706998 | 0.77 | ESR1 (0.75) | ESR1ESR2PDCD1CD274ALDH1A1 | |
| SCHEMBL14135698 | 0.77 | ESR1 (0.68) | ESR1ESR2PDCD1CD274ALDH1A1 | |
| Cyanate SCHEMBL4069262 | 0.76 | ESR1 (0.76) | ESR1ESR2PDCD1CD274ALDH1A1 | |
| SCHEMBL4145904 | 0.76 | MEN1 (0.38) | ESR1ESR2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL4160843 | 0.76 | ALOX5 (0.41) | ESR1ESR2ALDH1A1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527140-A | Synthesis method of 2, 3-bis (4-hydroxyphenyl) propionitrile | 石家庄圣泰化工有限公司 | 2021-10-22 | — | — | CN | claimed |
| US-7109274-B2 | Polyarylate compositions | GENERAL ELECTRIC COMPANY (US) | 2006-09-19 | — | — | US | claimed |
| JP-3271280-A | — | — | None | — | — | JP | disclosed |
| CN-119264366-A | Halogen-free intrinsic flame-retardant waterborne polyurethane material and preparation method thereof | 中原工学院 | 2025-01-07 | — | — | CN | disclosed |
| CN-113527140-A | Synthesis method of 2, 3-bis (4-hydroxyphenyl) propionitrile | 石家庄圣泰化工有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-113527140-A | Synthesis method of 2, 3-bis (4-hydroxyphenyl) propionitrile | 石家庄圣泰化工有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-113527140-A | Synthesis method of 2, 3-bis (4-hydroxyphenyl) propionitrile | 石家庄圣泰化工有限公司 | 2021-10-22 | — | — | CN | disclosed |
| WO-2021116820-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BENOXAPROFEN | AUROBINDO PHARMA LIMITED (IN) | 2021-06-17 | — | — | WO | disclosed |
| CN-111566206-A | Derivation of somatotropin cells from stem cells and uses thereof | 纪念斯隆-凯特琳癌症中心 | 2020-08-21 | — | — | CN | disclosed |
| US-9512437-B2 | Genetic mutations that disrupt dhurrin production in sorghum | PURDUE RESEARCH FOUNDATION (US) | 2016-12-06 | — | — | US | disclosed |
| US-9289752-B2 | Catalyst for reacting carboxylic acid nitriles | EVONIK RÖHM GMBH (DE) | 2016-03-22 | — | — | US | disclosed |
| EP-0485173-A2 | Esters and amides of substituted fused ring phenyl acetic acids | FGN, INC. (US) | 1992-05-13 | — | — | EP | disclosed |
| JP-H03271280-A | BETA-(P-HYDROXYPHENYL)PROPIOGUANAMINE AND PRODUCTION THEREOF | HITACHI CHEM CO LTD | 1991-12-03 | — | — | JP | disclosed |
| US-5059610-A | QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-10-22 | — | — | US | disclosed |
| US-4920132-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4083847-A | Transiently water-soluble disperse mono-azo dyes containing a diamino-methylene-carbacyl group | CIBA-GEIGY CORPORATION (US) | 1978-04-11 | — | — | US | disclosed |
| US-4066830-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
| US-4051166-A | Araliphatic diisocyanates | THE UPJOHN COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
| US-3987026-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1976-10-19 | — | — | US | disclosed |
| US-3979506-A | Radioactive compounds for labeling proteins | PIERCE CHEMICAL COMPANY (US) | 1976-09-07 | — | — | US | disclosed |