Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 7/20 | 0.48 |
| ▸ | KDM5A | P29375 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM7A | Q6ZMT4 | 2/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | PHF2 | O75151 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4501301 | 1.00 | EYA3 (0.57) | EYA3PTPN1TTRTHRATHRB | |
| SCHEMBL4501314 | 0.86 | PTPN1 (0.60) | EYA3PTPN1TTRTHRATHRB | |
| SCHEMBL4501308 | 0.86 | PTPN1 (0.60) | EYA3PTPN1TTRTHRATHRB | |
| SCHEMBL4501311 | 0.86 | PTPN1 (0.60) | EYA3PTPN1TTRTHRATHRB | |
| SCHEMBL27992957 | 0.79 | EYA3 (0.80) | EYA3PTPN1TTRTHRATHRB | |
| SCHEMBL2944813 | 0.78 | PTPN1 (0.69) | EYA3PTPN1TTRTHRATHRB | |
| Hydrochloric Acid SCHEMBL9347277 | 0.77 | PTPN1 (0.67) | EYA3PTPN1TTRTHRATHRB | |
| SCHEMBL31314625 | 0.77 | EYA3 (0.67) | EYA3PTPN1TTRTHRATHRB | |
| SCHEMBL2943743 | 0.77 | PTPN1 (0.67) | EYA3PTPN1TTRTHRATHRB | |
| SCHEMBL11785448 | 0.77 | EYA3 (0.64) | EYA3PTPN1TTRTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20060194851-A1 | Benzofuran compound and medicinal composition containing the same | NEW INDUSTRY RESEARCH ORGANIZATION, THE (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1627873-A1 | BENZOFURAN COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | The New Industry Research Organization (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194851-A1 | Benzofuran compound and medicinal composition containing the same | LTB4R2, LTC4S, LTB4R | EYA3 3724/4885PTPN1 2108/4885TTR 4369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.