SCHEMBL4501445

SCHEMBL4501445

Cc1cc(Cl)ccc1S(=O)(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.50
TRPV4 Q9HBA0 1/20 0.43
FLT1 P17948 1/20 0.42
FLT4 P35916 1/20 0.42
KDR P35968 1/20 0.42
GRIK1 P39086 1/20 0.42
GRIK2 Q13002 1/20 0.42
IDH1 O75874 5/20 0.41
ALDH1A1 P00352 2/20 0.40
CDK1 P06493 1/20 0.39
CCNB1 P14635 1/20 0.39
CCNA2 P20248 1/20 0.39
CDK2 P24941 1/20 0.39
CDK7 P50613 1/20 0.39
CCNH P51946 1/20 0.39
CCNA1 P78396 1/20 0.39
CYP3A4 P08684 1/20 0.39
KCNJ6 P48051 1/20 0.39
KCNJ5 P48544 1/20 0.39
KCNJ3 P48549 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3919077 0.98 GAA (0.49) GAATRPV4FLT1FLT4KDR
SCHEMBL231273 0.83 CDK1 (0.50) IDH1ALDH1A1CDK1CCNB1CCNA2
SCHEMBL251514 0.83 GAA (0.62) GAATRPV4FLT1FLT4KDR
SCHEMBL2122763 0.83 GAA (0.62) GAATRPV4FLT1FLT4KDR
SCHEMBL10576789 0.82 SRD5A2 (0.43) GAA
Hydrochloric Acid SCHEMBL11523644 0.82 CDK1 (0.49) IDH1ALDH1A1CDK1CCNB1CCNA2
Hydrochloric Acid SCHEMBL11164287 0.82 CDK1 (0.49) IDH1ALDH1A1CDK1CCNB1CCNA2
SCHEMBL1199760 0.81 TRPV4 (0.58) GAATRPV4FLT1FLT4KDR
SCHEMBL8405133 0.81 L3MBTL1 (0.59) GAATRPV4FLT1FLT4KDR
SCHEMBL29948957 0.81 TRPV4 (0.58) GAATRPV4FLT1FLT4KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5364925-A Epoxy resin advanced with a dihydric phenol and further chain extended with an additional dihydric phenol for use in electrical laminates THE DOW CHEMICAL COMPANY (US) 1994-11-15 US claimed
EP-0342532-B1 PROCESS FOR THE PREPARATION OF 4-CHLORO-2-METHYL-5-NITRO-PHENOL Wella Aktiengesellschaft (DE) 1993-01-07 EP claimed
EP-0507271-A2 Epoxy resin compositions for use in electrical laminates THE DOW CHEMICAL COMPANY (US) 1992-10-07 EP claimed
EP-0497284-A2 Epoxy resin compositions for use in electrical laminates THE DOW CHEMICAL COMPANY (US) 1992-08-05 EP claimed
US-4960955-A Process for making 4-chloro-2-methyl-5-nitro-phenol WELLA AKTIENGESELLSCHAFT (DE) 1990-10-02 US claimed
EP-0342532-A1 Process for the preparation of 4-chloro-2-methyl-5-nitro-phenol Wella Aktiengesellschaft (DE) 1989-11-23 EP claimed
EP-1636300-B1 NANOPOROUS LAMINATES DOW GLOBAL TECHNOLOGIES LLC (US) 2015-12-23 EP disclosed
EP-2792705-A2 Nanoporous laminates Dow Global Technologies LLC (US) 2014-10-22 EP disclosed
US-7485362-B2 Nanoporous laminates DOW GLOBAL TECHNOLOGIES INC. (US) 2009-02-03 US disclosed
EP-1636300-A2 NANOPOROUS LAMINATES DOW GLOBAL TECHNOLOGIES INC. (US) 2006-03-22 EP disclosed
US-20050158556-A1 A heat-degradable, curable organic resin having a thermolabile functionality thermally degradable to form a poromeric material having a low dielectric constant; matrix for a fiber-reinforced composite for electrical circuits; varnishes; controlled dispersion and size or pores; close porosity; workability BLUE CUBE IP LLC 2005-07-21 US disclosed
US-6855738-B2 Nanoporous laminates DOW GLOBAL TECHNOLOGIES INC. (US) 2005-02-15 US disclosed
WO-2004113427-A2 NANOPOROUS LAMINATES DOW GLOBAL TECHNOLOGIES INC. (US) 2004-12-29 WO disclosed
US-5206427-A Process for the preparation of aromatic (di)chlorosulphonic acids and (di)bromosulphonic acids BAYER AKTIENGESELLSCHAFT (DE) 1993-04-27 US disclosed
EP-0342532-B1 PROCESS FOR THE PREPARATION OF 4-CHLORO-2-METHYL-5-NITRO-PHENOL Wella Aktiengesellschaft (DE) 1993-01-07 EP disclosed
EP-0507271-A2 Epoxy resin compositions for use in electrical laminates THE DOW CHEMICAL COMPANY (US) 1992-10-07 EP disclosed
EP-0497284-A2 Epoxy resin compositions for use in electrical laminates THE DOW CHEMICAL COMPANY (US) 1992-08-05 EP disclosed
US-4960955-A Process for making 4-chloro-2-methyl-5-nitro-phenol WELLA AKTIENGESELLSCHAFT (DE) 1990-10-02 US disclosed
EP-0342532-A1 Process for the preparation of 4-chloro-2-methyl-5-nitro-phenol Wella Aktiengesellschaft (DE) 1989-11-23 EP disclosed
US-4139530-A CATIONIC DYES BAYER AKTIENGESELLSCHAFT (DE) 1979-02-13 US disclosed