Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506249 | 0.79 | MEN1 (0.45) | MEN1KMT2APDK2 | |
| SCHEMBL38660687 | 0.77 | TDP1 (0.41) | MEN1KMT2ACCNE2CDK2CCND3 | |
| SCHEMBL4558101 | 0.76 | RAB9A (0.48) | MEN1KMT2APDK2 | |
| SCHEMBL2344035 | 0.74 | MEN1 (0.39) | MEN1KMT2ACCNE2CDK2CCND3 | |
| SCHEMBL31142510 | 0.74 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL3418732 | 0.74 | MEN1 (0.39) | MEN1KMT2ACCNE2CDK2CCND3 | |
| SCHEMBL1714750 | 0.74 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL661200 | 0.74 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL10035871 | 0.74 | MEN1 (0.39) | MEN1KMT2ACCNE2CDK2CCND3 | |
| SCHEMBL5460906 | 0.74 | MEN1 (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592188-B2 | environmentally sensitive fluorescent dye covalently linked to a binding domain which has specific affinity for a target molecule; fluorescence resonance energy transfer; detecting changes in the binding, conformational change; detecting human immunodeficiency virus | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-09-22 | — | — | US | disclosed |
| US-20060029946-A1 | Live cell biosensors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-02-09 | — | — | US | disclosed |