SCHEMBL661200

SCHEMBL661200

CC1=Nc2ccc(O)cc2C1(C)C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
OPRM1 P35372 10/20 0.33
OPRD1 P41143 5/20 0.33
OPRK1 P41145 5/20 0.33
MRGPRX2 Q96LB1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31142510 1.00 MEN1 (0.39) MEN1KMT2AESR1ESR2CASP3
SCHEMBL21552111 0.85 NPSR1 (0.36) MEN1KMT2AESR1ESR2CASP3
SCHEMBL5850402 0.84 ESR1 (0.47) ESR1ESR2
SCHEMBL10035871 0.81 MEN1 (0.39) MEN1KMT2ACASP3RAB9AATM
SCHEMBL101511 0.80 TDP1 (0.41) MEN1KMT2ACASP3RAB9AATM
SCHEMBL38660687 0.80 TDP1 (0.41) MEN1KMT2ACASP3RAB9AATM
SCHEMBL15026849 0.78 CASP3 (0.36) MEN1KMT2ACASP3RAB9AATM
SCHEMBL3418732 0.77 MEN1 (0.39) MEN1KMT2ACASP3RAB9AATM
SCHEMBL1714750 0.77 MEN1 (0.39) MEN1KMT2A
SCHEMBL29869219 0.75 RXRA (0.37) MEN1KMT2ATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700690-A Spiropyran photo-induced power generation nano material and preparation method thereof 四川大学 2024-03-15 CN claimed
US-4062865-A Process for the synthesis of substituted indolenines SNAMPROGETTI S.P.A. (IT) 1977-12-13 US claimed
EP-4680677-A1 BENZOTHIENOPYRROLE CYANINE DYES Beckman Coulter, Inc. (US) 2026-01-21 EP disclosed
WO-2024196805-A1 BENZOTHIENOPYRROLE CYANINE DYES BECKMAN COULTER, INC. (US) 2024-09-26 WO disclosed
CN-117700690-A Spiropyran photo-induced power generation nano material and preparation method thereof 四川大学 2024-03-15 CN disclosed
US-20230248832-A1 Small Molecule Ligand-Drug Conjugates for Targeted Cancer Therapy UNIV EMORY (US) 2023-08-10 US disclosed
US-20230250126-A1 Indodicarbocyanine Phosphoramidites with Bathochromically Shifted Absorption and Emission, and Tunable Hydrophobicity THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2023-08-10 US disclosed
US-20230248832-A1 Small Molecule Ligand-Drug Conjugates for Targeted Cancer Therapy UNIV EMORY (US) 2023-08-10 US disclosed
CN-116332923-A Carbazole and phenazine compound meso-position substituted cyanine dye, and preparation method and application thereof 大连理工大学 2023-06-27 CN disclosed
US-11077210-B2 Near-infrared fluorescent contrast bioimaging agents and methods of use thereof BETH ISRAEL DEACONESS MEDICAL CENTER (US) 2021-08-03 US disclosed
CN-110054632-A A kind of two-step method prepares the synthetic method of 5 '-bromo alkoxy spiro-pyrans class compounds 青岛科技大学 2019-07-26 CN disclosed
US-20080318336-A1 Labels, Their Production Process And Their Uses LABORATOIRES SYNTH-INNOVE (FR) 2008-12-25 US disclosed
WO-2007017602-A2 MARQUEURS, LEUR PROCEDE DE FABRICATION ET LEURS APPLICATIONS LABORATOIRES SYNTH-INNOVE (FR) 2007-02-15 WO disclosed
EP-1227786-B1 AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE WELLA AG (DE) 2005-08-24 EP disclosed
US-6652601-B2 For dyeing and subsequently decolorizing fibers such as keratin fibers WELLA AKTIENGESELLSCHAFT (DE) 2003-11-25 US disclosed
US-20030079301-A1 Agent for dyeing fibers comprising an indoline/indolium derivative WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2003-05-01 US disclosed
EP-1227786-A1 AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE Wella Aktiengesellschaft (DE) 2002-08-07 EP disclosed
WO-2001062219-A1 AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE WELLA AKTIENGESELLSCHAFT (DE) 2001-08-30 WO disclosed
US-5473068-A Photochromic spirooxazine monomers and polysiloxanes YEDA RESEARCH AND DEVELOPMENT CO. LTD. AT THE WEIZMANN INSTITUTE OF SCIENCE (IL) 1995-12-05 US disclosed
US-5322945-A Photochromic spirooxazine monomers and polysiloxanes YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1994-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230248832-A1 Small Molecule Ligand-Drug Conjugates for Targeted Cancer Therapy SELL, EPCAM, SELPLG MEN1 1311/4885KMT2A 782/4885ESR1 105/4885
US-11077210-B2 Near-infrared fluorescent contrast bioimaging agents and methods of use thereof CD68, MSR1, CD47 MEN1 498/4885KMT2A 4412/4885ESR1 3047/4885
US-20030079301-A1 Agent for dyeing fibers comprising an indoline/indolium derivative IDO1, IDO2, KIT MEN1 1860/4885KMT2A 719/4885ESR1 4731/4885
US-20230250126-A1 Indodicarbocyanine Phosphoramidites with Bathochromically Shifted Absorption and Emission, and Tunable Hydrophobicity NT5C3B, PCNA, POLL MEN1 3049/4885KMT2A 2805/4885ESR1 2952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.