Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4503577

C=CCOC(=O)C(CC(=O)O)S(=O)(=O)O.N

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 13/20 0.35
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
RECQL P46063 1/20 0.32
TSHR P16473 1/20 0.32
MAPT P10636 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1077784 0.98 CASP1 (0.36) CASP1CYP3A4TDP1RECQLTSHR
SCHEMBL27766572 0.98 CASP1 (0.36) CASP1CYP3A4TDP1RECQLTSHR
SCHEMBL87407 0.98 CASP1 (0.36) CASP1CYP3A4TDP1RECQLTSHR
Sulfuric Acid SCHEMBL9815941 0.96 CASP1 (0.35) CASP1CYP3A4TDP1RECQLTSHR
SCHEMBL2937128 0.96 CASP1 (0.35) CASP1CYP3A4TDP1RECQLTSHR
SCHEMBL6418321 0.96 CASP1 (0.35) CASP1CYP3A4TDP1RECQLTSHR
SCHEMBL5457190 0.96 CASP1 (0.35) CASP1CYP3A4TDP1RECQLTSHR
Ethylene SCHEMBL5962491 0.96 CASP1 (0.35) CASP1CYP3A4TDP1RECQLTSHR
SCHEMBL28432001 0.90 CASP1 (0.33) CASP1CYP3A4
Monoethanolamine SCHEMBL10816531 0.88 CASP1 (0.32) CASP1MAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1220886-B1 LIQUID CLEANSING COMPOSITION COMPRISING LAMELLAR PHASE HAVING LOW SALT LEVEL UNILEVER PLC (GB) 2014-03-05 EP claimed
EP-1607471-B2 Extrudable multiphase composition comprising lamellar phase inducing structurant in each phase UNILEVER PLC (GB) 2013-08-21 EP claimed
EP-1607471-B1 Extrudable multiphase composition comprising lamellar phase inducing structurant in each phase UNILEVER PLC (GB) 2009-11-25 EP claimed
EP-1607471-A1 Extrudable multiphase composition comprising lamellar phase inducing structurant in each phase UNILEVER PLC (GB) 2005-12-21 EP claimed
EP-1267825-B1 EXTRUDABLE MULTIPHASE COMPOSITION COMPRISING A LAMELLAR PHASE AND AN ISOTROPIC PHASE UNILEVER PLC (GB) 2005-11-02 EP claimed
US-6534456-B2 Cleaning compounds; storage stability UNILEVER HOME AND PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-03-18 US claimed
US-6534457-B2 Cleaning compounds; storage stability UNILEVER HOME AND PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-03-18 US claimed
US-6426326-B1 SURFACTANT MIXTURE UNILEVER HOME & PERSON CARE USA, A DIVISION OF CONOPCO, INC. 2002-07-30 US claimed
EP-1220886-A1 LIQUID CLEANSING COMPOSITION COMPRISING LAMELLAR PHASE HAVING LOW SALT LEVEL UNILEVER PLC (GB) 2002-07-10 EP claimed
US-20020010111-A1 Extrudable multiphase composition comprising lamellar phase inducing structurant in each phase UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-01-24 US claimed
US-20020010110-A1 Extrudable multiphase composition comprising a lamellar phase and an isotropic phase UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-01-24 US claimed
WO-2001019949-A1 LIQUID CLEANSING COMPOSITION COMPRISING LAMELLAR PHASE HAVING LOW SALT LEVEL UNILEVER PLC (GB) 2001-03-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010111-A1 Extrudable multiphase composition comprising lamellar phase inducing structurant in each phase ABHD6, AQP1, LIPA CASP1 3147/4885CYP3A4 4564/4885TDP1 1192/4885
US-20020010110-A1 Extrudable multiphase composition comprising a lamellar phase and an isotropic phase PIK3C2A, ABHD6, PIK3C2G CASP1 4050/4885CYP3A4 4714/4885TDP1 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.