SCHEMBL4504028

SCHEMBL4504028

CCN(CC)C(=O)C=C(C)c1cc2cccc(OC(c3ccccc3)c3ccccc3)c2o1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 15/20 0.55
LTB4R2 Q9NPC1 15/20 0.55
RXRA P19793 3/20 0.43
RARA P10276 1/20 0.43
LMNA P02545 1/20 0.42
RECQL P46063 1/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
RXRB P28702 1/20 0.41
RXRG P48443 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4504025 1.00 LTB4R (0.55) LTB4RLTB4R2RXRARARALMNA
SCHEMBL4504027 1.00 LTB4R (0.55) LTB4RLTB4R2RXRARARALMNA
SCHEMBL4352255 0.91 LTB4R (0.63) LTB4RLTB4R2RXRARARALMNA
SCHEMBL4352260 0.91 LTB4R (0.63) LTB4RLTB4R2RXRARARALMNA
SCHEMBL4507305 0.88 LTB4R (0.47) LTB4RLTB4R2RXRARARALMNA
SCHEMBL4507308 0.88 LTB4R (0.47) LTB4RLTB4R2RXRARARALMNA
SCHEMBL4507310 0.88 LTB4R (0.47) LTB4RLTB4R2RXRARARALMNA
SCHEMBL4503385 0.80 LTB4R (0.55) LTB4RLTB4R2
SCHEMBL4503383 0.80 LTB4R (0.55) LTB4RLTB4R2
SCHEMBL4503389 0.80 LTB4R (0.55) LTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638540-B2 Benzofuran compound and medicinal composition containing the same THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) 2009-12-29 US disclosed
US-20060194851-A1 Benzofuran compound and medicinal composition containing the same NEW INDUSTRY RESEARCH ORGANIZATION, THE (JP) 2006-08-31 US disclosed
EP-1627873-A1 BENZOFURAN COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME The New Industry Research Organization (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060194851-A1 Benzofuran compound and medicinal composition containing the same LTB4R2, LTC4S, LTB4R LTB4R 3/4885LTB4R2 1/4885RXRA 4558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.