Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 17/20 | 0.63 |
| ▸ | LTB4R2 | Q9NPC1 | 17/20 | 0.63 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4352255 | 1.00 | LTB4R (0.63) | LTB4RLTB4R2RXRARARALMNA | |
| SCHEMBL4504025 | 0.91 | LTB4R (0.55) | LTB4RLTB4R2RXRARARALMNA | |
| SCHEMBL4504027 | 0.91 | LTB4R (0.55) | LTB4RLTB4R2RXRARARALMNA | |
| SCHEMBL4504028 | 0.91 | LTB4R (0.55) | LTB4RLTB4R2RXRARARALMNA | |
| SCHEMBL4507305 | 0.89 | LTB4R (0.47) | LTB4RLTB4R2RXRARARALMNA | |
| SCHEMBL4507310 | 0.89 | LTB4R (0.47) | LTB4RLTB4R2RXRARARALMNA | |
| SCHEMBL4507308 | 0.89 | LTB4R (0.47) | LTB4RLTB4R2RXRARARALMNA | |
| SCHEMBL4504776 | 0.87 | RXRA (0.52) | LTB4RLTB4R2RXRARARALMNA | |
| SCHEMBL4504773 | 0.87 | RXRA (0.52) | LTB4RLTB4R2RXRARARALMNA | |
| SCHEMBL4504774 | 0.87 | RXRA (0.52) | LTB4RLTB4R2RXRARARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084492-B2 | Benzofuran compound and pharmaceutical composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2011-12-27 | — | — | US | claimed |
| US-20090124687-A1 | Benzofuran Compound and Pharmaceutical Composition Containing the Same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-05-14 | — | — | US | claimed |
| US-8084492-B2 | Benzofuran compound and pharmaceutical composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2011-12-27 | — | — | US | disclosed |
| US-20090124687-A1 | Benzofuran Compound and Pharmaceutical Composition Containing the Same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124687-A1 | Benzofuran Compound and Pharmaceutical Composition Containing the Same | LTB4R2, LTB4R, LTC4S | LTB4R 2/4885LTB4R2 1/4885RXRA 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.