Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4504876 | 0.93 | MRGPRX4 (0.49) | SMN1; SMN2ALDH1A1LRRK2KDM4ESCD5 | |
| SCHEMBL4502765 | 0.88 | SCD5 (0.54) | SMN1; SMN2ALDH1A1KDM4ESCD5MEN1 | |
| SCHEMBL4508842 | 0.87 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1KDM4ESCD5MEN1 | |
| SCHEMBL4492919 | 0.86 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1KDM4ESCD5MEN1 | |
| SCHEMBL4504870 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1KDM4ESCD5MEN1 | |
| SCHEMBL4509650 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1KDM4ESCD5MEN1 | |
| SCHEMBL4492672 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1KDM4ESCD5MEN1 | |
| Hydrochloric Acid SCHEMBL4512405 | 0.83 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KDM4ESCD5MEN1 | |
| SCHEMBL4496073 | 0.80 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1KDM4ESCD5MEN1 | |
| SCHEMBL4508426 | 0.80 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KDM4ESCD5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | claimed |
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | SMN1; SMN2 2075/4885ALDH1A1 1311/4885LRRK2 949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.