Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 15/20 | 0.44 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KIF23 | Q02241 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EEF2K | O00418 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4484748 | 0.84 | KIF11 (0.63) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL4493304 | 0.84 | KIF11 (0.60) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL4498257 | 0.84 | KIF11 (0.43) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL4500235 | 0.83 | GHSR (0.35) | KIF11ROCK2EEF2K | |
| SCHEMBL4500050 | 0.82 | KIF11 (0.52) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL4500793 | 0.82 | KIF11 (0.42) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL4502944 | 0.81 | KIF11 (0.42) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL4511153 | 0.81 | KIF11 (0.45) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL4490308 | 0.81 | KIF11 (0.52) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL4501628 | 0.79 | KIF11 (0.62) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476743-B2 | Compounds, compositions, and methods | CYTOKINETICS, INC. (US) | 2009-01-13 | — | — | US | claimed |