Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.54 |
| ▸ | BCHE | P06276 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.54 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209834 | 0.90 | ACHE (0.59) | ACHEBCHEALDH1A1HSD17B10TSHR | |
| SCHEMBL9736603 | 0.89 | ACHE (0.62) | ACHEBCHEALDH1A1HSD17B10TSHR | |
| SCHEMBL9738344 | 0.77 | ACHE (0.69) | ACHEBCHEALDH1A1HSD17B10TSHR | |
| SCHEMBL10653208 | 0.76 | ACHE (0.58) | ACHEBCHEALDH1A1HSD17B10TSHR | |
| SCHEMBL9208760 | 0.76 | ACHE (0.57) | ACHEBCHEGRIN1GRIN2ALMNA | |
| SCHEMBL4502500 | 0.76 | ACHE (0.62) | ACHEBCHEALDH1A1HSD17B10TSHR | |
| SCHEMBL9597376 | 0.73 | BCHE (0.51) | ACHEBCHEALDH1A1HSD17B10TSHR | |
| SCHEMBL9597374 | 0.73 | BCHE (0.51) | ACHEBCHEALDH1A1HSD17B10TSHR | |
| SCHEMBL9171253 | 0.73 | KMT2A (0.59) | ACHEBCHEALDH1A1KDM4ECYP1A2 | |
| SCHEMBL10653266 | 0.73 | ACHE (0.51) | ACHEBCHEALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311303-B1 | 4-aminopyridine derivatives | PFIZER (US) | 1995-05-24 | — | — | EP | claimed |
| EP-0287977-B1 | Fused heteroalkylene quinolinamines, a process and intermediates for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1994-06-29 | — | — | EP | claimed |
| US-5112830-A | Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | claimed |
| WO-1989002740-A1 | 4-AMINOPYRIDINE DERIVATIVES | PFIZER INC. (US) | 1989-04-06 | — | — | WO | claimed |
| WO-1989002739-A1 | 4-AMINOPYRIDINE DERIVATIVES | PFIZER INC. (US) | 1989-04-06 | — | — | WO | claimed |
| EP-0287977-A2 | Fused heteroalkylene quinolinamines, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-10-26 | — | — | EP | claimed |
| US-8252814-B2 | Agents and crystals for improving excretory potency of urinary bladder | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-08-28 | — | — | US | disclosed |
| US-20090264467-A1 | Agents and crystals for improving excretory potency of urinary bladder | ISHIHARA YUJI | 2009-10-22 | — | — | US | disclosed |
| EP-1891954-A2 | Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder | Takeda Pharmaceutical Company Limited (JP) | 2008-02-27 | — | — | EP | disclosed |
| US-20070021391-A1 | Preventive/remedy for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-25 | — | — | US | disclosed |
| US-20060281725-A1 | Agents and crystals for improving excretory potency of urinary bladder | ISIHARA YUJI | 2006-12-14 | — | — | US | disclosed |
| EP-1640021-A1 | PREVENTIVE/REMEDY FOR URINARY DISTURBANCE | Takeda Pharmaceutical Company Limited (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1604653-A1 | Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder | Takeda Pharmaceutical Company Limited (JP) | 2005-12-14 | — | — | EP | disclosed |
| US-5002955-A | Pyrroloquinolines for enhancement of memory | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4843079-A | ALZHEIMER*S DISEASE | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0311303-A2 | 4-aminopyridine derivatives | PFIZER INC. (US) | 1989-04-12 | — | — | EP | disclosed |
| WO-1989002740-A1 | 4-AMINOPYRIDINE DERIVATIVES | PFIZER INC. (US) | 1989-04-06 | — | — | WO | disclosed |
| WO-1989002739-A1 | 4-AMINOPYRIDINE DERIVATIVES | PFIZER INC. (US) | 1989-04-06 | — | — | WO | disclosed |
| EP-0287977-A2 | Fused heteroalkylene quinolinamines, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-10-26 | — | — | EP | disclosed |
| EP-0268871-A1 | Quinoline derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021391-A1 | Preventive/remedy for urinary disturbance | ACHE, BCHE, CHAT | ACHE 1/4885BCHE 2/4885ALDH1A1 346/4885 |
| US-20090264467-A1 | Agents and crystals for improving excretory potency of urinary bladder | ACHE, BCHE, PDE7A | ACHE 1/4885BCHE 2/4885ALDH1A1 1143/4885 |
| US-20060281725-A1 | Agents and crystals for improving excretory potency of urinary bladder | ACHE, BCHE, PDE7A | ACHE 1/4885BCHE 2/4885ALDH1A1 1245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.