Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.57 |
| ▸ | BCHE | P06276 | 7/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651092 | 0.92 | ACHE (0.62) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL10653208 | 0.82 | ACHE (0.58) | ACHEBCHEGRIN1GRIN2ALMNA | |
| SCHEMBL9207530 | 0.77 | ACHE (0.66) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL4506044 | 0.76 | ACHE (0.54) | ACHEBCHEGRIN1GRIN2ALMNA | |
| SCHEMBL10654307 | 0.74 | ACHE (0.66) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL10654771 | 0.74 | ACHE (0.63) | ACHEBCHEGRIN1GRIN2ALMNA | |
| SCHEMBL9583084 | 0.73 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2ALMNA | |
| SCHEMBL8019759 | 0.73 | ACHE (0.94) | ACHEBCHEGRIN1GRIN2ALMNA | |
| SCHEMBL9583887 | 0.72 | ACHE (0.97) | ACHEBCHEGRIN1GRIN2ALMNA | |
| SCHEMBL9211865 | 0.72 | ACHE (0.62) | ACHEBCHEGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311303-B1 | 4-aminopyridine derivatives | PFIZER (US) | 1995-05-24 | — | — | EP | claimed |
| WO-1989002740-A1 | 4-AMINOPYRIDINE DERIVATIVES | PFIZER INC. (US) | 1989-04-06 | — | — | WO | claimed |
| WO-1989002739-A1 | 4-AMINOPYRIDINE DERIVATIVES | PFIZER INC. (US) | 1989-04-06 | — | — | WO | claimed |
| EP-0311303-B1 | 4-aminopyridine derivatives | PFIZER (US) | 1995-05-24 | — | — | EP | disclosed |
| US-5202440-A | Certain 9-amino-2-(or 4)-oxa 1,2,3,4-tetrahydro- or 1,2,3,4,5,6,7,8-octahydro-acridines | PFIZER INC. (US) | 1993-04-13 | — | — | US | disclosed |
| CN-1032440-A | The 4-aminopyridine derivatives class | PFIZER (US) | 1989-04-19 | — | — | CN | disclosed |
| EP-0311303-A2 | 4-aminopyridine derivatives | PFIZER INC. (US) | 1989-04-12 | — | — | EP | disclosed |
| WO-1989002739-A1 | 4-AMINOPYRIDINE DERIVATIVES | PFIZER INC. (US) | 1989-04-06 | — | — | WO | disclosed |
| WO-1989002740-A1 | 4-AMINOPYRIDINE DERIVATIVES | PFIZER INC. (US) | 1989-04-06 | — | — | WO | disclosed |
| EP-0268871-A1 | Quinoline derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-06-01 | — | — | EP | disclosed |