Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6330054 | 0.76 | MEN1 (0.51) | POLBMEN1KMT2A | |
| SCHEMBL6745681 | 0.76 | MEN1 (0.40) | POLBAOC3LMNAMEN1KMT2A | |
| SCHEMBL6745678 | 0.76 | KDM4E (0.41) | POLBAOC3MEN1KMT2APPARG | |
| Hydrogen Peroxide SCHEMBL27864054 | 0.68 | HRH1 (0.54) | AOC3LMNAMEN1KMT2A | |
| SCHEMBL1837685 | 0.68 | TSHR (0.52) | POLBAOC3LMNAMEN1KMT2A | |
| SCHEMBL28491387 | 0.68 | ALDH1A1 (0.39) | LMNAMEN1KMT2A | |
| SCHEMBL8488783 | 0.68 | ALDH1A1 (0.54) | MEN1KMT2AADRB2PPARG | |
| SCHEMBL16824139 | 0.67 | ALDH1A1 (0.47) | POLBAOC3LMNAMEN1KMT2A | |
| SCHEMBL27449474 | 0.66 | L3MBTL1 (0.45) | POLBLMNAMEN1KMT2A | |
| SCHEMBL107889 | 0.66 | HRH1 (0.56) | AOC3LMNAMEN1KMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689383-A4 | NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS | METABASIS THERAPEUTICS INC (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1689383-A2 | NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS | Metabasis Therapeutics, Inc. (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005051298-A2 | NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS | METABASIS THERAPEUTICS, INC. (US) | 2005-06-09 | — | — | WO | disclosed |