Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | SCD | O00767 | 11/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 10/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.40 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4504473 | 0.88 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MRGPRX4SCDSCD5 | |
| SCHEMBL4505284 | 0.87 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1SCDSCD5 | |
| Hydrochloric Acid SCHEMBL4508956 | 0.86 | SCD5 (0.52) | SMN1; SMN2ALDH1A1MRGPRX4SCDSCD5 | |
| SCHEMBL4493419 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1SCDSCD5HPGD | |
| SCHEMBL4501251 | 0.83 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MRGPRX4SCDSCD5 | |
| Hydrochloric Acid SCHEMBL4512405 | 0.83 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1SCDSCD5HPGD | |
| SCHEMBL4507518 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1SCDSCD5HPGD | |
| SCHEMBL4507671 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1SCDSCD5KMT2A | |
| SCHEMBL23241871 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1SCDSCD5HPGD | |
| SCHEMBL4504477 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MRGPRX4SCDSCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | SMN1; SMN2 2075/4885ALDH1A1 1311/4885MRGPRX4 1550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.