Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 8/20 | 0.45 |
| ▸ | CTSS | P25774 | 5/20 | 0.45 |
| ▸ | CTSB | P07858 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401961 | 0.92 | CASP1 (0.51) | CTSKCASP1CTSLCTSB | |
| SCHEMBL6182119 | 0.86 | CTSK (0.61) | CTSKCASP1CTSLCTSSCTSB | |
| SCHEMBL1802007 | 0.86 | CTSK (0.61) | CTSKCASP1CTSLCTSSCTSB | |
| SCHEMBL29877959 | 0.86 | CTSK (0.61) | CTSKCASP1CTSLCTSSCTSB | |
| SCHEMBL22657972 | 0.86 | CASP1 (0.60) | CASP1 | |
| SCHEMBL22657970 | 0.86 | CASP1 (0.60) | CASP1 | |
| SCHEMBL17177676 | 0.86 | KLK7 (0.51) | CTSKCASP1CTSLCTSSCTSB | |
| SCHEMBL2584726 | 0.86 | KLK7 (0.51) | CTSKCASP1CTSLCTSSCTSB | |
| SCHEMBL27919626 | 0.85 | CTSK (0.57) | CTSKCASP1CTSLCTSSCTSB | |
| SCHEMBL11232429 | 0.84 | CASP1 (0.48) | CTSKCASP1CTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3122743-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES | Azevan Pharmaceuticals, Inc. (US) | 2017-02-01 | — | — | EP | disclosed |
| WO-2015148962-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES | AZEVAN PHARMACEUTICALS, INC. (US) | 2015-10-01 | — | — | WO | disclosed |
| EP-2587919-A1 | METHODS FOR TREATING POST TRAUMATIC STRESS DISORDER | Azevan Pharmaceuticals, Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012003436-A1 | METHODS FOR TREATING POST TRAUMATIC STRESS DISORDER | AZEVAN PHARMACEUTICALS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |