Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11871546 | 0.82 | POLB (0.59) | MAPTCYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL26357112 | 0.81 | MAPT (0.67) | MAPTCYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL5251522 | 0.78 | MAPT (0.70) | MAPTCYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL4513935 | 0.78 | CYP2D6 (0.53) | CYP2C9CYP2C19POLBALDH1A1KMT2A | |
| SCHEMBL152680 | 0.78 | MAPT (0.70) | MAPTCYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL26357044 | 0.77 | MAPT (1.00) | MAPTCYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL4749191 | 0.77 | ALDH1A1 (0.71) | MAPTCYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL28394042 | 0.75 | SMN1; SMN2 (0.61) | MAPTCYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL8129380 | 0.75 | ALDH1A1 (0.69) | MAPTCYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL11730441 | 0.75 | MAPT (0.65) | MAPTCYP2C9CYP2C19POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3932452-A | 1-Arylmethyl-2-imidazolidinones | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-01-13 | — | — | US | claimed |
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1864971-A1 | PROPHYLACTIC/THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2007-12-12 | — | — | EP | disclosed |
| US-3932452-A | 1-Arylmethyl-2-imidazolidinones | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | MAPT 4692/4885CYP2C9 597/4885CYP2C19 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.