SCHEMBL450960

SCHEMBL450960

O=C(Cc1ccc(O)cc1)C(O)Cc1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.56
CA2 P00918 2/20 0.52
CAMK2A Q9UQM7 1/20 0.52
SLC7A5 Q01650 1/20 0.48
FNTA P49354 1/20 0.47
FNTB P49356 1/20 0.47
ESR1 P03372 5/20 0.46
ESR2 Q92731 5/20 0.46
TAAR1 Q96RJ0 3/20 0.44
CTBP2 P56545 1/20 0.43
KDM6B O15054 1/20 0.42
SHBG P04278 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL176064 0.93 FNTA (0.59) SLC6A2CA2CAMK2ASLC7A5FNTA
SCHEMBL16431461 0.93 FNTA (0.59) SLC6A2CA2CAMK2ASLC7A5FNTA
SCHEMBL13960330 0.88 SLC6A2 (0.54) SLC6A2CA2CAMK2ASLC7A5FNTA
SCHEMBL107523 0.86 ESR1 (0.49) SLC6A2CA2CAMK2ASLC7A5FNTA
SCHEMBL107899 0.82 CA2 (0.50) SLC6A2CA2CAMK2ASLC7A5FNTA
SCHEMBL454095 0.82 CES2 (0.52) SLC6A2SLC7A5
SCHEMBL108840 0.79 CA2 (0.47) SLC6A2CA2CAMK2AFNTAFNTB
SCHEMBL107420 0.79 TAAR1 (0.48) SLC6A2SLC7A5ESR1ESR2TAAR1
SCHEMBL2148366 0.79 SLC6A2 (0.49) SLC6A2SLC7A5ESR1ESR2TAAR1
SCHEMBL235131 0.79 KDM6B (0.63) SLC6A2CA2CAMK2ASLC7A5FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
US-12054761-B2 Rapid pretreatment Apalta Patents OÜ (EE) 2024-08-06 US disclosed
US-11821047-B2 High pressure zone formation for pretreatment Apalta Patent OÜ (EE) 2023-11-21 US disclosed
US-20230295678-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2023-09-21 US disclosed
EP-4098750-A1 RAPID PRETREATMENT Sweetwater Energy, Inc. (US) 2022-12-07 EP disclosed
EP-3230463-B1 RAPID PRETREATMENT SWEETWATER ENERGY INC (US) 2022-05-25 EP disclosed
US-11332723-B2 Engineered microorganisms for production of commodity chemicals and cellular biomass THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-17 US disclosed
WO-2011008564-A2 COMPOSITIONS AND METHODS FOR IMPROVED SACCHARIFICATION OF BIOMASS QTEROS, INC. (US) 2011-01-20 WO disclosed
US-20100298611-A1 PRODUCTION OF FERMENTIVE END PRODUCTSFROM CLOSTRIDIUM sp. QTEROS, INC. (US) 2010-11-25 US disclosed
US-20100279354-A1 ADAPTING MICROORGANISMS FOR AGRICULTURAL PRODUCTS EVOLUGATE, LLC (US) 2010-11-04 US disclosed
US-20100268000-A1 Compositions and Methods for Fermentation of Biomass QTEROS, INC. (US) 2010-10-21 US disclosed
US-20100086981-A1 COMPOSITIONS AND METHODS FOR IMPROVED SACCHARIFICATION OF BIOMASS QTEROS, INC. (US) 2010-04-08 US disclosed
US-20090203089-A1 ISOLATED ALCOHOL DEHYDROGENASE ENZYMES AND USES THEREOF BIO ARCHITECTURE LAB, INC. (US) 2009-08-13 US disclosed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US disclosed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US disclosed
WO-2009046370-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA SLC6A2 4843/4885CA2 3146/4885CAMK2A 4018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.