Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | PNMT | P11086 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064178 | 0.82 | NR4A2 (0.56) | NR4A2KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8068789 | 0.82 | NR4A2 (0.56) | NR4A2KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27521186 | 0.79 | NR4A2 (0.53) | NR4A2KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2989427 | 0.79 | KDM4E (0.49) | NR4A2LOXL2PNMTKDM4ESMN1; SMN2 | |
| SCHEMBL13977538 | 0.79 | PSMD14 (0.56) | NR4A2LOXL2KDM4ESMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL263934 | 0.77 | HTR1A (0.54) | LOXL2KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL29410781 | 0.77 | NR4A2 (0.68) | NR4A2KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL318769 | 0.77 | NR4A2 (0.68) | NR4A2KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10009591 | 0.76 | NR4A2 (1.00) | NR4A2KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7503075 | 0.74 | NR4A2 (0.47) | NR4A2KDM4ESMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029855-A1 | Quinoline Derivatives and Their Use as Pesticides | BASF SE (DE) | 2009-01-29 | — | — | US | disclosed |
| EP-2007727-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS PESTICIDES | BASF SE (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007104726-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS PESTICIDES | BASF SE (DE) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029855-A1 | Quinoline Derivatives and Their Use as Pesticides | CBR3, HCRTR1, HCAR3 | NR4A2 480/4885LOXL2 1077/4885PNMT 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.