Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15053528 | 1.00 | TSHR (0.48) | TSHRALDH1A1F7F3FAAH | |
| SCHEMBL195771 | 0.77 | TSHR (0.52) | TSHRALDH1A1 | |
| SCHEMBL516006 | 0.77 | TSHR (0.38) | TSHRALDH1A1F7F3FAAH | |
| SCHEMBL516005 | 0.77 | TSHR (0.38) | TSHRALDH1A1F7F3FAAH | |
| SCHEMBL6006373 | 0.76 | TSHR (0.41) | TSHRALDH1A1F7F3FAAH | |
| SCHEMBL29617234 | 0.75 | TSHR (0.36) | TSHRALDH1A1F7F3FAAH | |
| SCHEMBL11861443 | 0.71 | DNM1 (0.42) | TSHRFAAHTRPV1 | |
| SCHEMBL4042668 | 0.71 | TSHR (0.44) | TSHRALDH1A1FAAH | |
| SCHEMBL516425 | 0.71 | TSHR (0.41) | TSHRALDH1A1F7F3FAAH | |
| SCHEMBL6432081 | 0.71 | TSHR (0.82) | TSHRALDH1A1F7F3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079824-B2 | Method for the synthesis of an amino acetal | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-07-14 | — | — | US | disclosed |
| US-20130165682-A1 | METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-06-27 | — | — | US | disclosed |
| WO-2012005693-A1 | METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165682-A1 | METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL | AOX1, DAO, ALDH7A1 | TSHR 3830/4885ALDH1A1 11/4885F7 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.