Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4525282 | 0.90 | OPRM1 (0.48) | OPRM1ALDH1A1TDP1TP53GABRP | |
| SCHEMBL4530850 | 0.90 | OPRM1 (0.48) | OPRM1ALDH1A1TDP1TP53GABRP | |
| SCHEMBL4528214 | 0.83 | — | — | |
| SCHEMBL4531321 | 0.77 | OPRM1 (0.50) | OPRM1ALDH1A1TDP1TP53GABRP | |
| SCHEMBL4526000 | 0.77 | OPRM1 (0.39) | OPRM1ALDH1A1TDP1TP53GABRP | |
| SCHEMBL2062083 | 0.76 | OPRM1 (0.48) | OPRM1ALDH1A1TDP1TP53GABRP | |
| SCHEMBL317886 | 0.73 | — | — | |
| SCHEMBL1012485 | 0.73 | OPRM1 (0.75) | OPRM1ALDH1A1TDP1TP53GABRP | |
| SCHEMBL14654820 | 0.73 | — | — | |
| SCHEMBL22838164 | 0.72 | OPRM1 (0.57) | OPRM1ALDH1A1TDP1TP53GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273726-B2 | Compositions for treating and/or preventing diseases characterized by the presence of metal ions | BRANDEIS UNIVERSITY (US) | 2012-09-25 | — | — | US | disclosed |
| US-20100184724-A1 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF METAL IONS | GRENPHARMA LLC (US) | 2010-07-22 | — | — | US | disclosed |
| US-7595308-B2 | Treatment and/or prevention of Alzheimer's disease, other neurodegenerative diseases, and/or diseases characterized by the presence of certain metal ions, by using organosilicon compounds such as dichlorodiethylsilane | GRENPHARMA LLC (US) | 2009-09-29 | — | — | US | disclosed |
| US-20090203644-A1 | Compositions for treating and/or preventing diseases characterized by the presence of metal ions | GRENPHARMA LLC (US) | 2009-08-13 | — | — | US | disclosed |
| US-7507480-B2 | Corrosion-resistant metal surfaces | BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) | 2009-03-24 | — | — | US | disclosed |
| US-20060269760-A1 | Corrosion-resistant metal surfaces | ENERGY, UNITED STATES DEPARTMENT OF | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184724-A1 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF METAL IONS | FABP2, SLC3A2, SLC40A1 | OPRM1 2260/4885ALDH1A1 1931/4885TDP1 4794/4885 |
| US-20090203644-A1 | Compositions for treating and/or preventing diseases characterized by the presence of metal ions | APP, PSEN1, IAPP | OPRM1 4807/4885ALDH1A1 4682/4885TDP1 1013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.