Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.90 |
| ▸ | XBP1 | P17861 | 1/20 | 0.90 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.90 |
| ▸ | RAB9A | P51151 | 11/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.67 |
| ▸ | TP53 | P04637 | 10/20 | 0.67 |
| ▸ | NPC1 | O15118 | 10/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490857 | 0.94 | MAPT (1.00) | MAPTXBP1HIF1ARAB9ASMN1; SMN2 | |
| SCHEMBL2489033 | 0.86 | MAPT (0.71) | MAPTXBP1HIF1ARAB9ASMN1; SMN2 | |
| SCHEMBL2491850 | 0.83 | MAPT (0.70) | MAPTXBP1HIF1ARAB9ASMN1; SMN2 | |
| SCHEMBL2488984 | 0.83 | MAPT (0.75) | MAPTXBP1HIF1ARAB9ASMN1; SMN2 | |
| SCHEMBL2493940 | 0.81 | MAPT (0.69) | MAPTXBP1HIF1ARAB9ASMN1; SMN2 | |
| SCHEMBL4502780 | 0.80 | MAPT (0.66) | MAPTXBP1HIF1ARAB9ASMN1; SMN2 | |
| SCHEMBL2242337 | 0.80 | MAPT (0.66) | MAPTXBP1HIF1ARAB9ASMN1; SMN2 | |
| SCHEMBL2242897 | 0.78 | MAPT (1.00) | MAPTXBP1HIF1ARAB9ASMN1; SMN2 | |
| SCHEMBL4514393 | 0.78 | MAPT (0.60) | MAPTXBP1HIF1ARAB9ASMN1; SMN2 | |
| SCHEMBL4513561 | 0.78 | MAPT (0.60) | MAPTXBP1HIF1ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-10-15 | — | — | US | disclosed |
| EP-1933834-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007042816-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | IL4I1, EPX, IL4 | MAPT 270/4885XBP1 208/4885HIF1A 1220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.