Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30001924 | 0.86 | HSD17B10 (0.56) | HSD17B10TSHRLMNAALDH1A1KDM4E | |
| SCHEMBL2589891 | 0.86 | HSD17B10 (0.56) | HSD17B10TSHRLMNAALDH1A1KDM4E | |
| SCHEMBL1663175 | 0.86 | HSD17B10 (0.60) | HSD17B10TSHRLMNAALDH1A1KDM4E | |
| SCHEMBL6295397 | 0.84 | TSHR (0.58) | HSD17B10TSHRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL27796780 | 0.83 | HSD17B10 (0.56) | HSD17B10LMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28747080 | 0.81 | KMT2A (0.53) | HSD17B10LMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8373001 | 0.81 | TSHR (0.55) | TSHRALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL6291402 | 0.81 | TSHR (0.55) | HSD17B10TSHRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL1470136 | 0.81 | TSHR (0.55) | TSHRALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30068941 | 0.81 | TSHR (0.55) | HSD17B10TSHRLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111440077-B | Synthesis method of 2, 5-diaminophenylethanol sulfate and application thereof in antiallergic hair dye | 上海舒尔发化妆品科技有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-111440077-A | Synthesis method of 2, 5-diaminophenylethanol sulfate and application thereof in anti-allergic hair dye | 上海舒尔发化妆品科技有限公司 | 2020-07-24 | — | — | CN | disclosed |
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | PLE PATRICK | 2009-02-05 | — | — | US | disclosed |
| EP-1802608-A1 | QUINAZOLINE DERIVATIVES FOR USE AGAINST CANCER | AstraZeneca AB (SE) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040526-A1 | QUINAZOLINE DERIVATIVES FOR USE AGAINST CANCER | ASTRAZENECA AB (SE) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | AQP3, AQP1, F12 | HSD17B10 4746/4885TSHR 2524/4885LMNA 1025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.