Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 10/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2984162 | 0.81 | CHRM3 (0.56) | CHRM3CHRM2LMNAKCNH2CHRM1 | |
| Hydrochloric Acid SCHEMBL30448099 | 0.80 | CHRM3 (0.55) | CHRM3CHRM2LMNAKCNH2CHRM1 | |
| SCHEMBL29882115 | 0.80 | CHRM3 (0.50) | CHRM3CHRM2LMNAKCNH2CHRM1 | |
| SCHEMBL4138872 | 0.80 | CHRM3 (0.54) | CHRM3CHRM2LMNAKCNH2CHRM1 | |
| SCHEMBL18248596 | 0.79 | CHRM3 (0.54) | CHRM3CHRM2LMNAKCNH2CHRM1 | |
| SCHEMBL18248486 | 0.79 | CHRM3 (0.54) | CHRM3CHRM2LMNAKCNH2CHRM1 | |
| SCHEMBL7643094 | 0.79 | CHRM3 (0.54) | CHRM3CHRM2LMNAKCNH2CHRM1 | |
| SCHEMBL17749475 | 0.78 | CHRM3 (0.53) | CHRM3CHRM2LMNAKCNH2CHRM1 | |
| SCHEMBL9295790 | 0.78 | CHRM3 (0.59) | CHRM3CHRM2LMNAKCNH2CHRM1 | |
| SCHEMBL9426385 | 0.77 | CHRM3 (0.52) | CHRM3CHRM2LMNAKCNH2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233920-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-09-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233920-A1 | ORGANIC COMPOUNDS | REN, ACE, AGTR1 | CHRM3 1261/4885CHRM2 1252/4885LMNA 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.