SCHEMBL4514023

SCHEMBL4514023

CCCC(CN)[Si](O)(O)CCC

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
NFKB1 P19838 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4533769 0.71 ALDH1A1 (0.41)
SCHEMBL4522571 0.70 OPRM1 (0.38) CYP3A4
SCHEMBL4531008 0.68 SPHK1 (0.39) CYP3A4TSHR
SCHEMBL4515291 0.68 SPHK1 (0.39) CYP3A4TSHR
SCHEMBL4523094 0.68 SPHK1 (0.39) CYP3A4TSHR
SCHEMBL4524378 0.65
SCHEMBL8582383 0.65 ALDH1A1 (0.30)
SCHEMBL14378855 0.60 TSHR (0.32) TSHR
SCHEMBL14129166 0.59 CYP3A4 (0.30) CYP3A4TSHRNFKB1NPSR1
SCHEMBL9744572 0.59 ALDH1A1 (0.37) CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507480-B2 Corrosion-resistant metal surfaces BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) 2009-03-24 US disclosed
US-20060269760-A1 Corrosion-resistant metal surfaces ENERGY, UNITED STATES DEPARTMENT OF 2006-11-30 US disclosed