SCHEMBL4533769

SCHEMBL4533769

CCCCC(CN)[Si](O)(O)CC

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA2 P00918 3/20 0.33
CA1 P00915 2/20 0.33
DPP4 P27487 1/20 0.32
DPP9 Q86TI2 1/20 0.32
DPP7 Q9UHL4 1/20 0.32
FDPS P14324 1/20 0.31
DNM1 Q05193 2/20 0.31
MAPK1 P28482 1/20 0.30
OPRM1 P35372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4522571 0.94 OPRM1 (0.38) ALDH1A1TDP1FDPSOPRM1
SCHEMBL4515291 0.92 SPHK1 (0.39) ALDH1A1DNM1OPRM1
SCHEMBL4523094 0.92 SPHK1 (0.39) ALDH1A1DNM1OPRM1
SCHEMBL4531008 0.92 SPHK1 (0.39) ALDH1A1DNM1OPRM1
SCHEMBL4514023 0.71 CYP3A4 (0.30)
SCHEMBL555053 0.68 ALDH1A1 (0.40) ALDH1A1TDP1DNM1OPRM1
SCHEMBL9744580 0.67 ALDH1A1 (0.37) ALDH1A1TDP1CA2CA1FDPS
SCHEMBL9744572 0.67 ALDH1A1 (0.37) ALDH1A1TDP1CA2CA1FDPS
SCHEMBL4513263 0.67 OPRM1 (0.46) OPRM1
SCHEMBL4532158 0.65 SPHK1 (0.47) OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507480-B2 Corrosion-resistant metal surfaces BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) 2009-03-24 US disclosed
US-20060269760-A1 Corrosion-resistant metal surfaces ENERGY, UNITED STATES DEPARTMENT OF 2006-11-30 US disclosed