Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515991 | 0.96 | PIK3CA (0.35) | MAPK14PIK3CACSNK1DCSNK1EEGFR | |
| SCHEMBL4525365 | 0.91 | PIK3CA (0.38) | PIK3CACSNK1DCSNK1EKDM4ERPS6KA3 | |
| SCHEMBL4524040 | 0.87 | KDM4E (0.36) | MAPK14CSNK1DKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4516320 | 0.83 | FYN (0.37) | ALDH1A1FFAR4CDK2MAP4K4 | |
| SCHEMBL4509953 | 0.83 | FFAR4 (0.34) | MAPK14CSNK1DKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4512708 | 0.80 | SLC9A5 (0.37) | KDM4EALDH1A1L3MBTL1AURKB | |
| SCHEMBL4517455 | 0.78 | STK4 (0.40) | PIK3CAALDH1A1CDK2MAP4K4 | |
| SCHEMBL4525263 | 0.77 | CHEK1 (0.39) | MAPK14CSNK1DKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4514401 | 0.69 | CHRM2 (0.38) | MAPK14EGFRKDM4ERPS6KA3ALDH1A1 | |
| SCHEMBL4523437 | 0.68 | RPS6KA3 (0.41) | MAPK14CSNK1DCSNK1EKDM4ERPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625887-B2 | Receptor agonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-01 | — | — | US | disclosed |
| US-20060199795-A1 | Receptor agonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-09-07 | — | — | US | disclosed |
| EP-1591120-A1 | RECEPTOR AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2005-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199795-A1 | Receptor agonists | GPBAR1, GPR35, GPR55 | MAPK14 2270/4885PIK3CA 1478/4885CSNK1D 2824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.