Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | STK4 | Q13043 | 1/20 | 0.36 |
| ▸ | STK3 | Q13188 | 1/20 | 0.36 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | AURKAIP1 | Q9NWT8 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4525365 | 0.89 | PIK3CA (0.38) | SLC9A5KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL4525263 | 0.88 | CHEK1 (0.39) | SLC9A5KDM4EALDH1A1POLBLRRK2 | |
| SCHEMBL4515991 | 0.81 | PIK3CA (0.35) | KDM4EALDH1A1AURKBL3MBTL1 | |
| SCHEMBL4517455 | 0.80 | STK4 (0.40) | ALDH1A1LMNAPOLBLRRK2STK4 | |
| SCHEMBL4509953 | 0.80 | FFAR4 (0.34) | KDM4EALDH1A1LRRK2STK4STK3 | |
| SCHEMBL4514397 | 0.80 | MAPK14 (0.35) | KDM4EALDH1A1AURKBL3MBTL1 | |
| SCHEMBL4516320 | 0.73 | FYN (0.37) | ALDH1A1LMNAPOLBLRRK2STK4 | |
| SCHEMBL4520735 | 0.69 | NOTUM (0.41) | TDP1KDM4EALDH1A1LMNALRRK2 | |
| SCHEMBL8650234 | 0.68 | L3MBTL1 (0.46) | SLC9A5TDP1KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11786073 | 0.66 | KMO (0.44) | SLC9A5ALDH1A1LMNAPOLBLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625887-B2 | Receptor agonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-01 | — | — | US | disclosed |
| US-20060199795-A1 | Receptor agonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-09-07 | — | — | US | disclosed |
| EP-1591120-A1 | RECEPTOR AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2005-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199795-A1 | Receptor agonists | GPBAR1, GPR35, GPR55 | SLC9A5 499/4885TDP1 2569/4885KDM4E 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.