SCHEMBL451449

SCHEMBL451449

C=CC(C)n1c(=O)n(C(C)C=C)c(=O)n(C(C)C=C)c1=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278681 0.67 CYP3A4 (0.31) CYP3A4
SCHEMBL1318483 0.65 ALDH1A1 (0.42)
SCHEMBL4885676 0.65 TSHR (0.33)
SCHEMBL9352764 0.62 GPR3 (0.43) CYP3A4
SCHEMBL4801719 0.57
SCHEMBL128564 0.57
SCHEMBL25061686 0.56 ALDH1A1 (0.44)
SCHEMBL20151 0.55
SCHEMBL10794029 0.55
SCHEMBL423439 0.52 CYP3A4 (0.38) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11111326-B2 Highly fluorinated elastomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-09-07 US claimed
US-8906821-B2 Curing compositions for fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-12-09 US claimed
EP-2445939-A2 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M Innovative Properties Company (US) 2012-05-02 EP claimed
US-20120065321-A1 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2012-03-15 US claimed
US-7989552-B2 Improved compression set values, rheology, radiation transparency; environmentally friendly; reduced residues from organotin catalysts; phosphonium or ammonium perfluorodialkoxides, PTFE and PFA copolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-08-02 US claimed
WO-2010151610-A2 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-12-29 WO claimed
US-7666949-B2 Curing compositions for fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-02-23 US claimed
US-7592386-B2 Dual cure hydrotalcite containing fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-22 US claimed
EP-2084224-A1 DUAL CURE HYDROTALCITE CONTAINING FLUOROPOLYMER COMPOSITIONS 3M Innovative Properties Company (US) 2009-08-05 EP claimed
US-20090088517-A1 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2009-04-02 US claimed
US-20040072959-A1 Crosslinked elastomers using organonitrogen curing agents based on bis-amidine, tris-amidine, or tetra-amidine, or a salt thereof 3M INNOVATIVE PROPERTIES COMPANY 2004-04-15 US claimed
WO-2004020513-A1 FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-03-11 WO claimed
US-20040044139-A1 Fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY 2004-03-04 US claimed
WO-2004009660-A1 FLUOROPOLYMERS HAVING IMPROVED COMPRESSION SET 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-01-29 WO claimed
US-20040014900-A1 Fluoropolymers having improved compression set 3M INNOVATIVE PROPERTIES COMPANY 2004-01-22 US claimed
EP-1366094-A1 FLUOROPOLYMER COMPOSITIONS 3M Innovative Properties Company (US) 2003-12-03 EP claimed
US-6613846-B2 Fluoroelastomer with a cure site having a halogen capable of participation in a peroxide cure reaction and an organic peroxide 3M INNOVATIVE PROPERTIES COMPANY 2003-09-02 US claimed
US-20020177666-A1 Fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY 2002-11-28 US claimed
US-20020145228-A1 Fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY 2002-10-10 US claimed
WO-2002060969-A1 FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-08-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065321-A1 CURING COMPOSITIONS FOR FLUOROPOLYMERS POLQ, QPCTL, NQO2 CYP3A4 2483/4885
US-20090088517-A1 CURING COMPOSITIONS FOR FLUOROPOLYMERS QPCTL, NQO2, POLQ CYP3A4 3677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.