Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4523754 | 0.92 | CNR1 (0.43) | ALDH1A1LMNATSHRL3MBTL1KDM4E | |
| Trifluoroacetic Acid SCHEMBL4528182 | 0.92 | MCL1 (0.43) | ALDH1A1LMNATSHRKDM4EMAPT | |
| Trifluoroacetic Acid SCHEMBL4529169 | 0.91 | KDM4E (0.41) | ALDH1A1KDM4EMAPTMEN1HTT | |
| Trifluoroacetic Acid SCHEMBL4520540 | 0.91 | TPSAB1 (0.41) | ALDH1A1LMNATSHRL3MBTL1KDM4E | |
| Trifluoroacetic Acid SCHEMBL4523799 | 0.91 | KDM4E (0.41) | ALDH1A1KDM4EMAPTMEN1HTT | |
| Trifluoroacetic Acid SCHEMBL4515642 | 0.91 | KDM4E (0.43) | ALDH1A1KDM4EMAPTMEN1HTT | |
| Trifluoroacetic Acid SCHEMBL4521871 | 0.90 | KDM4E (0.40) | ALDH1A1LMNATSHRKDM4EMAPT | |
| Trifluoroacetic Acid SCHEMBL4515923 | 0.90 | MCL1 (0.44) | ALDH1A1LMNAKDM4EMAPTMEN1 | |
| Trifluoroacetic Acid SCHEMBL4527558 | 0.90 | HRH4 (0.42) | ALDH1A1KDM4EMAPTMEN1HTT | |
| Trifluoroacetic Acid SCHEMBL4531108 | 0.90 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275555-A1 | Substituted indole ligands for the ORL-1 receptor | BRANE DISCOVERY S.R.L. (IT) | 2009-11-05 | — | — | US | claimed |
| US-20090275555-A1 | Substituted indole ligands for the ORL-1 receptor | BRANE DISCOVERY S.R.L. (IT) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275555-A1 | Substituted indole ligands for the ORL-1 receptor | OGFRL1, OPRL1, ORMDL3 | ALDH1A1 395/4885LMNA 4213/4885TSHR 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.