SCHEMBL451457

SCHEMBL451457

C=C(C#N)C(=O)OC(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.52
CTSK P43235 5/20 0.34
DGAT1 O75907 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CTSS P25774 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL27987817 0.89 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL22426094 0.83 ALDH1A1 (0.48) ALDH1A1TSHR
SCHEMBL775782 0.81 ALDH1A1 (0.47) ALDH1A1TSHR
SCHEMBL10392485 0.79 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL11150709 0.79 ALDH1A1 (0.55) ALDH1A1TSHRTDP1
SCHEMBL9562013 0.78 TDP1 (0.46) ALDH1A1TSHRCTSKDGAT1TDP1
SCHEMBL5052850 0.77 DGAT1 (0.32) DGAT1
SCHEMBL8429717 0.77 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL4891441 0.77 ALDH1A1 (0.56) ALDH1A1TSHR
SCHEMBL3132337 0.75 ALDH1A1 (0.42) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4717744-A1 USE OF A COMPOSITION BASED ON CYANOACRYLATE AND (METH)ACRYLATE Bostik SA (FR) 2026-04-01 EP claimed
US-20250215132-A1 TWO-PART CURABLE COMPOSITION BOSTIK SA (FR) 2025-07-03 US claimed
EP-4504844-A1 TWO-PART CURABLE COMPOSITION Bostik SA (FR) 2025-02-12 EP claimed
US-20240240064-A1 TWO-PART CURABLE COMPOSITION BOSTIK SA (FR) 2024-07-18 US claimed
CN-118290637-A Method for manufacturing reinforced resin lens 丹阳奥尔帝光学眼镜有限公司 2024-07-05 CN claimed
EP-4334368-A1 TWO-PART CURABLE COMPOSITION Bostik SA (FR) 2024-03-13 EP claimed
CN-117377706-A Two-part curable composition 博斯蒂克股份公司 2024-01-09 CN claimed
US-11813375-B2 Therapeutic agent for solid cancer YANCHERS INC. (JP) 2023-11-14 US claimed
WO-2023194367-A1 TWO-PART CURABLE COMPOSITION BOSTIK SA (FR) 2023-10-12 WO claimed
EP-4257648-A1 TWO-PART CURABLE COMPOSITION Bostik SA (FR) 2023-10-11 EP claimed
CN-1487983-A Cyanoacrylate compositions curable to flexible polymeric materials ���̩��(R&D)���޹�˾ 2004-04-07 CN claimed
US-20040013614-A1 Acrylic-based adhesive composition BTG INTERNATIONAL LIMITED (GB) 2004-01-22 US claimed
US-20030175229-A1 Electrophilic monomers for treating the hair L'OREAL (FR) 2003-09-18 US claimed
EP-1341563-A1 ACRYLIC-BASED ADHESIVE COMPOSITION UNIVERSIDAD DE ALICANTE (ES) 2003-09-10 EP claimed
WO-2003053380-A2 USE OF ELECTROPHILIC MONOMERS FOR HAIR TREATMENT L'OREAL (FR) 2003-07-03 WO claimed
WO-2002009784-A1 ACRYLIC-BASED ADHESIVE COMPOSITION UNIVERSIDAD DE ALICANTE (ES) 2002-02-07 WO claimed
EP-1100380-A1 BIOABSORBABLE BLENDS AND SURGICAL ARTICLES THEREFROM TYCO HEALTHCARE GROUP LP (US) 2001-05-23 EP claimed
WO-2000072761-A1 BIOABSORBABLE BLENDS AND SURGICAL ARTICLES THEREFROM TYCO HEALTH CARE GROUP, LP (US) 2000-12-07 WO claimed
US-4313865-A A Z-CYANOACRYLATE AND A 1,1-OISUBSTITUTED DIENE PROVIDES FLEXIBILITY, HEAT RESISTANCE, IMPACT RESISTANCE, PEEL RESISTANCE AND WATER RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-02-02 US claimed
EP-0026665-A1 Quick-setting adhesive composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-04-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030175229-A1 Electrophilic monomers for treating the hair NACA, SUCLG1, TYR ALDH1A1 176/4885TSHR 4584/4885CTSK 2853/4885
US-20040013614-A1 Acrylic-based adhesive composition C5AR1, C1R, COL2A1 ALDH1A1 980/4885TSHR 459/4885CTSK 3924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.